Exercise attenuates neuropathic pain and neuroinflammation in an obese rat model exhibiting diabetes-related metabolic dysfunction and features of type 2 diabetes.
This study aimed to investigate the effects and mechanisms of exercise intervention on neuropathic pain in an obese rat model exhibiting diabetes-related metabolic dysfunction. Chronic constriction injury (CCI) was induced in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, and the animals were rando…
"Seeing the dog will make me feel better even if I eat the cheese," animal-assisted interventions and impact on eating disorder treatment experience.
Some of the symptoms associated with eating disorders (EDs) have been previously treated through Animal Assisted Interventions (AAIs) in studies conducted with different populations and diseases. AAI may lead to benefits in relationships and treatment engagement. These variables are common vulnerabi…
Patient-Reported Continuity of GLP-1 Receptor Agonist Therapy.
Use of GLP-1 receptor agonists is associated with significant weight loss in many individuals. Discontinuation is associated with weight regain. Patients' experience with this is not well characterized. This study describes the patient experience of continuity of care. A cross-sectional electronic s…
Methyl eugenol increases neural microcirculation to promote nerve repair by regulating endothelial cell and Schwann cell communication via Ptn/Sdc4.
Neuromicrocirculatory disorders often accompany nerve injury. Improving neural microcirculation can promote the repair of injured nerves. Methyl eugenol is a major bioactive component of Asarum heterotropoides and has been reported to exert analgesic effects in chronic pain. This study aimed to demo…
Ossification of the Nuchal Ligament With Text Neck Syndrome.
Ossification of the nuchal ligament (ONL) is a common but frequently overlooked radiographic finding on lateral cervical spine imaging, characterized by ectopic bone formation within the nuchal ligament, most often at the C4/5 and C5/6 levels. Although usually asymptomatic, ONL has been associated w…
C2-C3 anterolisthesis with myelopathy in a toddler with Charcot-Marie-Tooth disease: a rare case and review of syndromic pediatric C2-C3 instability.
Cervical instability and myelopathy are rare in young children and are frequently overlooked, particularly in those with syndromic or neuromuscular disorders, in which motor delay may be misattributed to the underlying condition. Reported cases of C2-C3 instability are extremely uncommon and have pr…
Radiograph-based intervertebral sagittal translation-to-canal diameter ratio as a quantitative imaging marker for suspected lower cervical instability.
To compare radiographic differences between clinically suspected symptomatic lower cervical instability segments and asymptomatic normal segments and to evaluate the value of the radiograph-based intervertebral sagittal translation-to-canal diameter ratio (TCDR) as a quantitative imaging marker for…
Heterogeneous Cost Patterns of Episodic Recurrent Vestibular Vertigo in the Medicare Population: A Case-Control Economic Evaluation.
ObjectiveTo evaluate Medicare costs and healthcare usage with total annual payments comprising hospital, outpatient and prescription costs, neuroimaging, and vestibular and audiometric testing for benign paroxysmal vertigo (BPPV), Ménière's Disease (MD), and Vestibular Migraine (VM).Method…