Coarctation-like features from skeletal anomalies: recognising extrinsic compression in fetal echocardiography.
Prenatal diagnosis of coarctation of the aorta (CoA) remains a challenging diagnosis in fetal cardiology. In rare situations, extrinsic compression of the aorta can produce a pseudocoarctation-like appearance, characterised by elongation and kinking of the aorta. This appearance is rarely recognised…
Low Conus Position on Fetal MRI with Postnatal Correlation.
Abnormal low position of the conus medullaris on fetal MRI may portend tethered cord syndrome after birth. However, prenatal identification of low conus is challenging and frequently requires postnatal confirmation. This study aimed to compare two methods for evaluating conus position on fetal MRI b…
Tethered cord syndrome (TCS) is a neurodevelopmental disorder associated with neural tube defects (NTD), yet its genetic underpinnings remain poorly characterized. To elucidate its molecular basis, we conducted whole-exome sequencing (WES) on 81 TCS patients. Our analysis revealed that MNX1 variants…
Clinical and MR neuroimaging features of lumbosacral spinal malformations: a tertiary care institutional experience in south India.
Spinal dysraphisms are a group of malformations of the spinal cord or neural elements and the meninges with or without bony and soft tissue involvement due to defects in different stages of neural tube development. We aimed to study the clinico-radiological profile of spinal lumbosacral malformation…
Acupuncture as an Adjuvant Therapy for Tethered Cord Syndrome: A Case Report.
Tethered cord syndrome (TCS) is defined as a diverse clinical condition wherein excessive tension on the spinal cord produces a variety of symptoms and signs. Its clinical symptoms include motor deficits, deformities of the lower extremities, lower leg sensory deficits, pain in the lower extremities…
Bridging Clinical and Preclinical Perspectives on Spina Bifida and Tethered Cord Syndrome: Presentation, Neurogenic Bowel and Bladder Management, and Animal Models.
Although spina bifida (SB) and tethered cord syndrome (TCS) are often discussed and studied as separate conditions, their co-occurrence is common, clinically consequential, and understudied, particularly with respect to neurogenic bladder and bowel dysfunction. SB arises from incomplete neural tube…
Perioperative shear wave elastography for the evaluation of spinal cord release in pediatric dysraphism: first experience in 21 patients.
Shear wave elastography (SWE) is a recent method for evaluating soft tissue stiffness. Its application to the spinal cord is limited by the ultrasound bone barrier. Spinal dysraphism can cause neurological symptoms impairing bladder, bowel, and lower limb function due to a mechanical stress known as…