Laterality of fat distribution and its impact on tethered cord symptoms and surgical outcomes in pediatric spinal lipoma.
The aim of this study was to evaluate whether MRI-based anatomical factors, including fat lateralization and spinal cord rotation, are associated with postoperative retethering in pediatric spinal lipoma. This retrospective cohort study included pediatric patients (< 18 years old) who underwent spin…
Sacral extradural arteriovenous fistula in a filum terminale lipoma with retained medullary cord: illustrative case.
Sacral extradural arteriovenous fistula (AVF) associated with filum terminale (FT) is an extremely rare disease. Here, the authors report a progressive congestive myelopathy accompanied by tethered cord syndrome and lipoma. A 52-year-old woman who had a subcutaneous mass in the sacrococcygeal region…
Perioperative shear wave elastography for the evaluation of spinal cord release in pediatric dysraphism: first experience in 21 patients.
Shear wave elastography (SWE) is a recent method for evaluating soft tissue stiffness. Its application to the spinal cord is limited by the ultrasound bone barrier. Spinal dysraphism can cause neurological symptoms impairing bladder, bowel, and lower limb function due to a mechanical stress known as…
Is the bulbocavernosus reflex reliable under dexmedetomidine administration in children? -An analysis during tethered cord surgery.
Dexmedetomidine (DEX) is increasingly utilized in pediatric anesthesia; however, its impact on the bulbocavernosus reflex (BCR) remains unclear. The objective of this study was to elucidate the suppressive effects of DEX on the BCR and to establish a safe therapeutic window for its administration du…
Coarctation-like features from skeletal anomalies: recognising extrinsic compression in fetal echocardiography.
Prenatal diagnosis of coarctation of the aorta (CoA) remains a challenging diagnosis in fetal cardiology. In rare situations, extrinsic compression of the aorta can produce a pseudocoarctation-like appearance, characterised by elongation and kinking of the aorta. This appearance is rarely recognised…
Bridging Clinical and Preclinical Perspectives on Spina Bifida and Tethered Cord Syndrome: Presentation, Neurogenic Bowel and Bladder Management, and Animal Models.
Although spina bifida (SB) and tethered cord syndrome (TCS) are often discussed and studied as separate conditions, their co-occurrence is common, clinically consequential, and understudied, particularly with respect to neurogenic bladder and bowel dysfunction. SB arises from incomplete neural tube…
De novo chromatin remodelling variants in sporadic Chiari 1 malformation.
Chiari 1 malformation (CM1) is the most common congenital malformation of the human hindbrain. Although prior studies have implicated chromatin-remodeling genes in CM1, the de novo genetic architecture and underlying neurodevelopmental mechanisms remain incompletely defined. To investigate the molec…
Clinical and MR neuroimaging features of lumbosacral spinal malformations: a tertiary care institutional experience in south India.
Spinal dysraphisms are a group of malformations of the spinal cord or neural elements and the meninges with or without bony and soft tissue involvement due to defects in different stages of neural tube development. We aimed to study the clinico-radiological profile of spinal lumbosacral malformation…