Systematic review of diffusion tensor imaging in spina bifida myelomeningocele: clinical implications in the era of prenatal repair.
Spina bifida myelomeningocele (SBM) is a neural tube defect associated with altered brain development and impaired cognitive function. Structural brain abnormalities in SBM are well documented but less is known about potential white matter abnormalities. Diffusion tensor imaging (DTI) is a unique MR…
Trigeminal Neuralgia After a Cerebrospinal Fluid Leak: A Case Report.
Cerebrospinal fluid (CSF) leakage can be difficult to localize and may result in unexplained intracranial hypotension with intractable positional headache. Loss of CSF cushioning can cause brain sagging, leading to compression and traction of cranial nerves within the brain cisterns and mimicking Ch…
Pediatric complex Chiari I Malformation-how complex is it?
Pediatric complex Chiari I Malformation (CCM), defined by Chiari I with additional craniovertebral junction anomalies, has been associated with higher failure rates following foramen magnum decompression (FMD) alone, leading some to advocate occipitocervical fixation (OCF) or ventral decompression.…
An Unexpected Electrocardiogram in Congenital Heart Disease: A Rare Variant of a Common Cyanotic Syndrome.
A 19-year-old female with a history of tetralogy of Fallot (TOF) with prior right ventricle (RV)-pulmonary artery conduit, RV outflow tract aneurysm, intermittent ventricular arrhythmia, Chiari malformation, and scoliosis presented to establish care at our institution. Electrocardiogram (ECG) demons…
Long-Term Intracranial and Ophthalmologic Outcomes in Single Suture Craniosynostosis.
Long-term intracranial and ophthalmologic sequelae are incompletely characterized for single suture craniosynostosis at a population level. Prior studies are limited by small cohorts and short follow-up. A retrospective cohort study was performed using the Pediatric Health Information System (PHIS)…
From gene to geometry: the molecular morphogenesis of the fourth ventricle angle and its role in predicting brainstem dysfunction among Chiari I malformation patients.
Chiari malformation type 1 (CM-1) is traditionally defined by tonsillar herniation, yet clinical symptoms often correlate poorly with simple linear measurements. Emerging research suggests that the geometry of the fourth ventricle may reflect deeper developmental anomalies. This study aimed to evalu…
Pediatric hydrocephalus in Nigeria: a scoping review of management, treatment outcomes, and challenges.
Pediatric hydrocephalus continues to pose a significant neurosurgical challenge in Nigeria driven by delayed diagnosis, barriers to treatment, and loss to long-term follow-up. Systemic, infrastructural, and socioeconomic limitations in hydrocephalus care persist across sub-Saharan Africa (SSA) despi…