Wilkie syndrome combined with nutcracker syndrome presented as syncopal episodes: A case report.
Combined aortomesenteric compression is an extremely rare vascular condition where both the duodenum (Wilkie) and the left renal vein (nutcracker) are compressed between the aorta and the superior mesenteric artery (SMA). The causal factor is the abnormal course of the SMA originating from the abdom…
Central sensitization in long COVID: Associations with autonomic symptom burden, cerebral hypoperfusion, and neuroinflammation.
The mechanisms driving the broad spectrum of Long COVID symptoms-such as fatigue, brain fog, pain, and dysautonomia-remain uncertain. This study investigated central sensitization (CS) as a potential contributor to symptom burden in patients with Long COVID. We aimed to examine its association with…
Pragmatic approaches to improve the care of patients with sarcoidosis.
Sarcoidosis is associated with an increasing global burden, driven by rising prevalence, severe organ involvement, treatment-related morbidity, and substantial impairment in quality of life (QoL). Despite advances in diagnostics and therapeutics, important barriers continue to limit timely, equitabl…
dysautonomiasarcoidosissmall fiber neuropathybrain fog
Sex differences in brain functional connectivity changes to different energy densities of laser acupuncture at PC6 (Neiguan): a pilot resting-state fMRI study.
Purpose previous studies have suggested that laser acupuncture (LA) may influence autonomic nervous system (ANS) activity and brain functional connectivity (FC); however, the underlying neural mechanisms and potential sex-dependent responses remain to be further investigated. Using resting-state fun…
REenergizeME: intermittent hypoxia-hyperoxia treatment for myalgic encephalomyelitis/chronic fatigue syndrome-protocol for a randomised, placebo-controlled trial.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, disabling condition characterised by post-exertional malaise (PEM), autonomic dysfunction and markedly reduced quality of life. Its prevalence has increased following the COVID-19 pandemic, yet no effective disease-modifying t…
Longitudinal overview of symptomatic and immunosuppressive drugs in LEMS.
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune neuromuscular junction disorder characterized by muscle weakness and autonomic dysfunction. While amifampridine is the established first-line symptomatic treatment, longitudinal data regarding the evolution of therapeutic regimens over ti…
Rapid clinical stabilization following eculizumab therapy in severe anti-NMDAR encephalitis.
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a potentially severe autoimmune encephalitis that may rapidly progress to critical illness. We report a young patient with severe anti-NMDAR encephalitis complicated by seizures, psychiatric symptoms, behavioral disturbance, dyskinesia, and…
Does CANVAS mimic MSA-C? A prospective multimodal study.
AAGGG intronic expansions in RFC1 are responsible for Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS), but also ataxia associated to dysautonomia, parkinsonism and pyramidal syndrome, creating clinical overlap with multiple system atrophy of cerebellar type (MSA-C). Th…