Renal Denervation in Severe Neurogenic Dysautonomia: RANSOM Prospective Experience.
Severe neurogenic dysautonomia in advanced neurodegenerative disorders is characterized by extreme blood pressure variability (BPV), orthostatic instability, and recurrent syncopal events. Therapeutic options are limited, and these patients are commonly excluded from conventional hypertension trials…
Stüve-Wiedemann Syndrome (SWS) is a rare autosomal recessive skeletal dysplasia caused by variations in the leukemia inhibitory factor receptor (LIFR) gene. Due to its high rate of mortality in early life, current literature is largely limited to children with SWS. We present a case report of a…
Complexity analysis of heart rate variability: application to Holter monitoring in patients with hereditary angioedema due to C1 inhibitor deficiency.
Hereditary angioedema due to C1 inhibitor deficiency (HAE-C1INH) is a rare condition characterized by unpredictable swelling attacks. Despite evidence of the involvement of the cardiac autonomic nervous system in the pathophysiology of HAE-C1INH, no studies have been conducted under real-life condit…
Finding A Balance: Auricular Acupressure in the Allergy Clinic.
Auricular point acupressure (APA) is a simple technique related to acupuncture, which dates back to the 1950s, with acupuncture tools dating back thousands of years. The APA approach involves the short-term placement of beads or seeds to specific points on the external ear. In more recent times, aur…
Do Medications Actually Help in Patients with Postural Orthostatic Tachycardia Syndrome?: A Qualitative Study.
Postural orthostatic tachycardia syndrome (POTS) is a chronic autonomic disorder associated with debilitating symptoms. No medications have been approved for treatment, and patients commonly use off-label medications to treat symptoms. The hemodynamic implications of certain medication use have been…
Development of the long COVID - 6 dimensions quality of life (LC-6D-QoL) scale: a Delphi study.
Long COVID significantly impairs quality of life through multi-systemic complexity, including fatigue, cognitive dysfunction, and dysautonomia. Existing generic tools fail to capture these manifestations, limiting patient-centered assessment. To address this gap, this study proposed a patient-focuse…
SARS-CoV2 infection significantly increases the risk of cardiovascular events through multiple interconnected mechanisms including systemic inflammation, dysautonomia, endothelial dysfunction, and prothrombotic states. The endothelium plays a critical role in this increase in risk together with dysa…