Non-suicidal self-injury and suicide attempts among individuals seeking assessment for Ehlers-Danlos Syndromes.
Individuals with Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobility Spectrum Disorder (G-HSD) experience psychological distress and are at an increased risk for suicidal behaviors. The current study examined associations between factors uniquely relevant to this population and prior suicide…
Too high and too loose: dysautonomia and the hypertensive paradox in hypermobility disorders.
Hypertension in hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) represents an increasingly recognized but poorly understood clinical phenomenon. This review addresses the unique pathophysiology, diagnostic considerations, and management challenges of hypertension…
Patient-reported perspectives of a temporal relationship between autonomic dysfunction and mental health symptoms in a pediatric population.
Autonomic dysfunction, characterized by orthostatic intolerance and presyncope, is understudied in youth. Mental health comorbidities are commonly reported and sometimes blamed for the onset of autonomic dysfunction; however, no studies have yet examined this relationship. This study aimed to establ…
What Are We Treating? The Need for Broader Provider Understanding of POTS, Its Nature, and Care.
Postural orthostatic tachycardia syndrome (POTS) as conventionally defined is a chronic condition (typically >3 months duration) incorporating reproducible symptoms of orthostatic intolerance (including dizziness/lightheadedness, and near-syncope) in the absence of orthostatic hypotension (i.e., abs…
The Epidemiology and Clinical Presentation of the Acute Imbalance Syndrome (AIS)-A Systematic Review and Meta-Analysis.
The acute imbalance syndrome (AIS) refers to acute-onset and persistent vertigo, dizziness and/or imbalance without nystagmus, reflecting a subset of the acute vestibular syndrome (AVS) with or without nystagmus. While AVS with nystagmus is well characterized and the approach to these patients is va…
Nutritional Care of Patients with Parkinson's Disease.
There has been a growing interest in the nutritional care of patients with Parkinson's disease (PD). The nutritional domain can be considerably affected by the disease, its treatment, and progression, particularly by motor symptoms and levodopa-related complications, which are responsible for import…
Renal Denervation in Severe Neurogenic Dysautonomia: RANSOM Prospective Experience.
Severe neurogenic dysautonomia in advanced neurodegenerative disorders is characterized by extreme blood pressure variability (BPV), orthostatic instability, and recurrent syncopal events. Therapeutic options are limited, and these patients are commonly excluded from conventional hypertension trials…