Association of GLP-1 Receptor Agonist Use With Safety Outcomes in Individuals With Opioid Use Disorder: A Target Trial Emulation.
To evaluate the association between glucagon-like peptide-1 receptor agonist (GLP-1 RA) initiation and adverse gastrointestinal, renal, respiratory and psychiatric outcomes among individuals with opioid use disorder (OUD). This retrospective cohort study was conducted using the MarketScan Comme…
Examining a link between gastroparesis and anxiety and depression: a brief contemporary review.
Gastroparesis is a chronic gastrointestinal disorder characterized by delayed gastric emptying, often presenting with symptoms including nausea, vomiting, early satiety, and abdominal pain. Moreover, studies demonstrate higher rates of psychological distress among individuals with gastroparesis, com…
Long-term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow-up of over 20 years.
Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily affects female patients. There are scarce data evaluating the long-term outcomes in POTS. This study sought to evaluate the long-term impacts of POTS over multiple decades in adult patients.…
[Late complications after atrial fibrillation ablation : Diagnosis and management].
Delayed complications may occur up to weeks after atrial fibrillation (AF) ablation and are usually a consequence of initial injury during ablation and ongoing processes progressing to severe symptomatic but late-onset events. A structured clinical follow-up of patients to appraise for lat…
[Neural mechanism of acupuncture-driven vagus nerve-gastric reflex regulating gastric motility in mice with diabetic gastroparesis].
To observe the immediate regulatory effect of electroacupuncture (EA) on gastric motility via the vagus nerve in mice with diabetic gastroparesis (DGP), and to explore the potential central mechanism related to vagus nerve underlying the effects of acupoints. A total of 27 male C57BL/6 mice of clean…
Impact of gastric emptying and small intestinal carbohydrate absorption on glycemia in health and diabetes: therapeutic implications.
Gastric emptying, which exhibits a substantial inter-, but much lesser intraindividual, variation in health and is frequently disordered (particularly delayed) in diabetes, is now appreciated to be a major determinant of postprandial glycemia. The incretin hormones glucose dependent insulinotropic p…
Extreme Hyperlipasemia in End-Stage Renal Disease Mimicking Acute Pancreatitis: A Diagnostic Pitfall.
Marked elevations of pancreatic enzymes are commonly interpreted as evidence of acute pancreatitis. However, in patients with end-stage renal disease (ESRD), serum amylase and lipase may be elevated without pancreatic inflammation, posing a significant diagnostic challenge. We present a case illustr…