Gastrointestinal Manifestations of Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders: A Mentored Review.
Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder that is often diagnosed after diagnostic delays due to reliance on heightened clinical suspicion. Hypermobility spectrum disorders (HSD) bridge the gap between asymptomatic joint hypermobility and hEDS. Due to overlapping feat…
Esophageal Dysmotility and Gastroesophageal Reflux Disease Risk in Hypermobile Ehlers-Danlos Syndrome.
Individuals with hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorder (HSD) have an increased burden of foregut gastrointestinal symptoms, specifically dysphagia and reflux symptoms, versus non-hypermobile individuals. The overall aim of this study was to evaluate esophageal…
The prevalence of cardiac symptoms in Ehlers-Danlos syndrome and hypermobility spectrum disorder: a pilot study.
The authors compared palpitations, presyncope, syncope, and postural orthostatic tachycardia syndrome (POTS) prevalence among patients with hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorder (HSD). A retrospective analysis of patients referred for cardiac evaluation at the…
The lived experience of hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders in the United Kingdom: findings from a national cross-sectional survey.
This study explored the lived experiences of individuals with hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorder (HSD) in the United Kingdom, focusing on diagnosis, access to care, and impact on daily life. A cross-sectional, mixed-methods online survey was co-developed wi…
Comorbid Conditions of Ehlers-Danlos Syndromes and Vulvodynia: A Latent Class Analysis.
Having an Ehlers-Danlos syndrome (EDS) or hypermobility spectrum disorder (HSD) may increase the likelihood of vulvodynia six-fold. Studying vulvodynia in EDS/HSD may help identify causes of vulvodynia and potential treatments. Currently there are no consistently effective treatment methods for vulv…
Non-suicidal self-injury and suicide attempts among individuals seeking assessment for Ehlers-Danlos Syndromes.
Individuals with Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobility Spectrum Disorder (G-HSD) experience psychological distress and are at an increased risk for suicidal behaviors. The current study examined associations between factors uniquely relevant to this population and prior suicide…
An Overview of Vascular Compression Syndromes and Associations with Autonomic Dysfunction: A Review.
Background: Vascular compression syndromes are increasingly recognized as underdiagnosed contributors to morbidity in patients exhibiting dysautonomia. Underlying vascular compression syndromes affecting the head and neck, abdomen, pelvis, and lower extremities may influence venous return, neurohorm…
A clinical epidemiological study of musculoskeletal injury occurrence and orthopedic management patterns among individuals with hypermobility spectrum disorders.
To determine the frequency and clinical associations of hypermobility spectrum disorders in a central orthopedic hospital. A clinical epidemiological, prospective hospital-based cross-sectional design was employed. Kuwait Ministry of Health Ethics Board approved the study (ref. no. 2022/2233). The B…