Efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships.
This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medication use and complication rate as secondary endpoints, to evaluate the efficacy and safety of neural combing plus decompression guided by four neurovascular relationship subtypes for…
A prospective observational within-person MRI morphometric study comparing ictal and interictal brain volumes in status migrainosus.
To assess whether total masked brain volume differs during status migrainosus (SM) compared to post-SM interictal baseline using structural MRI. This prospective within-person study included 11 participants scanned during an SM attack and post-SM interictal baseline using T1-weighted MRI. FreeSurfer…
TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review).
Migraines are highly prevalent and disabling neurological disorders. Central sensitisation constitutes the core pathophysiological basis for its recurrent and chronic nature. Transient receptor potential vanilloid 1 (TRPV1), a key molecule in pain signalling, is not only involved in peripheral nocic…
Education Research: Educational Informatics: Characterizing Child Neurology Resident Clinical Experiences Using Electronic Health Record Data.
Gaps in preparedness for independent practice are common among recent graduates. Clinical experiences serve as the foundation for learning during residency, yet the breadth and variability of clinical exposure of child neurology residents remain poorly characterized. To inform programmatic curricula…
Headache is a common neurologic problem affecting many members of the population, including athletes. In athletes, headache is most likely a primary disorder, such as tension-type headache or migraine; however, athletes can be at a higher risk of secondary causes, such as posttraumatic headache. Thu…
Burden among participants with central disorders of hypersomnolence in six European countries.
Narcolepsy types 1 and 2 (NT1/NT2) and idiopathic hypersomnia (IH) are central disorders of hypersomnolence (CDHs) that significantly impact patients' quality of life (QoL). We investigated the recent medication use, comorbidities, and clinical burden among participants with CDHs from six European c…
Stroke mimics are conditions that resemble acute ischemic stroke, posing a major diagnostic challenge in time-sensitive care. Accurate differentiation is essential to prevent unnecessary thrombolysis, reduce costs, and avoid complications. Clinical assessment, scoring systems, and neuroimaging-parti…
Management of Vestibular Symptoms in Sports-Related Concussion.
Vestibular symptoms are common after sports-related concussion and predict slower recovery and delayed return to play. This review provides a practical, clinical profile-guided approach for clinicians. Early screening focuses on Vestibular/Ocular Motor Screen, timed tandem gait, and positional testi…