Patient reported trigger, not the speed of transition to continuous headache, is associated with headache-related disability in children: Results of a cross-sectional clinic-based study.
ObjectiveTo investigate the relationship between the evolution of continuous headache and headache-related disability in children.MethodsThis was a single site cross-sectional study using patient-entered questionnaires from children aged 6-17 who presented to neurology clinic between November 2022-M…
Long COVID Syndrome and Associated New Daily Persistent Headache (NDPH) Presenting With Crossed Clonus Response.
Evaluating patients following a COVID-19 infection with multiple chronic, progressive symptoms can be challenging, but easy to navigate by using the temporal profile obtained from the clinical history, findings from the neurological exam, and screening for red flag symptoms.
Steroid-Responsive, Post-infectious New Daily Persistent Headache With Mild Cerebrospinal Fluid Pleocytosis: A Case Report.
New daily persistent headache (NDPH) is a primary headache disorder characterized by a clearly remembered onset, with the headache becoming daily and unremitting within 24 hours and persisting for more than 3 months. Although antecedent infections have been reported as potential triggering events, t…
Brain networks activated when aggravating baseline chronic pain of an individual with new daily persistent headache: a case study.
In this study we examined neuronal mechanisms associated with chronic headache pain by recruiting a participant diagnosed with New Daily Persistent Headache (NDPH), who had the reliable characteristic that his baseline chronic pain could be immediately and consistently modulated (partially relieved…
Hallmarks of primary headache: part 4 - rare headache syndromes.
“Other primary headaches” is a group of heterogeneous headache disorders described in Chapter 4 of the third edition of the International Classification of Headache Disorders (ICHD-III). Due to the limited number of cases, most of these disorders are considered rare and represent a dia…
Abnormal brain iron deposition in patients with new daily persistent headache: a prospective quantitative susceptibility mapping study.
The underlying pathogenesis of New daily persistent headache (NDPH) is currently unknown. Abnormal iron deposition in specific brain regions has been reported to be associated with the pathogenesis of migraine. This study aimed to investigate the role of iron metabolism disorders in the pathogenesis…
7T multimodal MRI reveals structural-functional-quantitative susceptibility mapping abnormalities of new daily persistent headache.
New daily persistent headache (NDPH) is a rare, refractory primary headache with an unclear pathophysiological mechanism. Previous neuroimaging studies on NDPH have been largely limited to 3T MRI, which fails to thoroughly reveal microstructural changes, particularly subregional abnormalities and ir…
Epidemiology of new daily persistent headache: A systematic review and meta-analysis with comparison in regard to different age groups, sex, and patient sample settings.
This study aimed to synthesize the existing evidence and determine the prevalence of new daily persistent headache (NDPH) in relation to different population settings and age groups, evaluate sex-related patterns, and explore diagnostic challenges. NDPH is a rare primary headache disorder with poorl…