Efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships.
This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medication use and complication rate as secondary endpoints, to evaluate the efficacy and safety of neural combing plus decompression guided by four neurovascular relationship subtypes for…
Suzetrigine as a novel treatment for headache disorders: A case series.
Suzetrigine is a selective voltage-gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients r…
Endoscopic-Assisted Extended Nerve Decompression with Radical Artery Elimination Yields Superior Relief for Refractory Occipital Migraines.
Surgical decompression of the greater occipital nerve (GON) is a recognized treatment for occipital migraines that are resistant to medical management. Recent evidence suggests that vascular compression by the occipital artery (OA) contributes to occipital migraine pathophysiology. This study compar…
Our surgical experience in Arnold's neuralgia: Technical insights and clinical results.
Arnold's neuralgia, also referred to as greater occipital neuralgia, is a chronic neuropathic pain condition characterized by paroxysmal or continuous occipital pain. While most patients respond to conservative treatment, a subset develops medically refractory symptoms requiring surgical interventio…
Optimizing magnetic resonance imaging for detection of greater occipital nerve pathology in migraine headache disorders.
Migraine and occipital headache disorders are increasingly recognized as conditions that may rise from compression of extracranial peripheral nerves, particularly the greater occipital nerve (GON). Despite growing recognition of peripheral mechanisms contributing to headache pathophysiology, objecti…
Concussion symptoms are inherently nonspecific for concussion and many mimicking conditions exist. The biomechanics of the injury, the athlete's past medical history, their family history, and objective clinical examination tools must be included in the initial evaluation to improve diagnostic certa…
Neuropathic Cranial Pain Phenotypes After Craniotomy: A Large, Single-Center Retrospective Cohort Study.
Background and Objectives: Chronic headache after craniotomy is common and may include neuropathic subtypes (scar neuroma pain, occipital neuralgia). However, no large series has quantified these phenotypes. We conducted a single-center retrospective review (n = 5624 adult craniotomy patients) to es…
Regenerative Medicine Approaches to Craniofacial and Corneal Neuropathic Pain.
Craniofacial and corneal neuropathic pain are disabling conditions characterized by persistent pain that is frequently refractory to conventional pharmacologic and interventional therapies. These disorders arise from complex interactions between peripheral nerve injury, neuroinflammation, and malada…