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Chronic Pain

212 papers & discussions

Persistent pain lasting more than three months that affects daily functioning and quality of life.

Persistent painFatigueSleep disturbanceMood changesReduced mobilityBrain fog

Research

212
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PubMed

Factors predicting health-enhancing physical activity in patients with chronic widespread pain following a person-centred health plan.

Regular physical activity improves symptoms and overall health in people with chronic widespread pain. However, many struggle to stay active over time, highlighting the need for strategies that support long-term physical activity. To investigate if person-centred health plans that include physical a…

mslichen sclerosuschronic pain
PubMed

Efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships.

This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medication use and complication rate as secondary endpoints, to evaluate the efficacy and safety of neural combing plus decompression guided by four neurovascular relationship subtypes for…

mschronic painmigrainecervical instability
PubMed

Effects of Transcutaneous Electrical Nerve Stimulation, Electrical Muscle Stimulation, Exercise and Heat on Back Pain-A Randomized Controlled Clinical Exploratory Trial.

This randomized controlled study compared different forms of therapy for chronic back pain. Seventy-nine patients with chronic back pain with a duration of symptoms of more than 6 months were included in the study and randomly assigned to one of four therapy groups (a) sports therapy with a f…

lupusmschronic painlichen sclerosus
PubMed

Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain.

Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis-based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear. This study evaluate…

chronic paincervical instabilitymedian arcuatelichen sclerosus
PubMed

Prostatic vibratory stimulation for refractory chronic prostatitis: A case report.

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a challenging condition with limited effective treatments. We report a case of a 44-year-old man with refractory CP/CPPS treated with a home-based prostatic vibratory stimulation protocol. After 12 weeks, the NIH-CPSI score improved from…

chronic painpelvic pain
PubMed

Relationship Between Central Sensitization and Genetic Polymorphisms-A Case-Control Study in Fibromyalgia.

Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway. This study included 201 women with fibr…

fibromyalgiamschronic painlichen sclerosus
PubMed

Pulsed radiofrequency for treatment of complex regional pain syndrome: A scoping review.

Complex Regional Pain Syndrome (CRPS) is a debilitating chronic pain condition characterized by sensory, motor, and autonomic disturbances, often resistant to conventional therapies. Pulsed radiofrequency (PRF), a non-neurodestructive neuromodulation technique, has been described as a potential inte…

chronic paincomplex regional painlichen sclerosusantiphospholipid syndrome
PubMed

Thoracic sympathetic block with botulinum toxin A for complex regional pain syndrome: a retrospective case series.

Sympathetic interventions are frequently used in complex regional pain syndrome (CRPS). However, the evidence is inconclusive, and the response may depend on phenotype, anatomical target, and treatment durability. For upper-extremity CRPS, clinical data on thoracic sympathetic block (TSB) with botul…

chronic paincomplex regional pain

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