Efficacy analysis of combined nerve combing and decompression for occipital neuralgia based on the classification of neurovascular relationships.
This study set occipital pain improvement as the primary endpoint, and overall headache relief, migraine index, medication use and complication rate as secondary endpoints, to evaluate the efficacy and safety of neural combing plus decompression guided by four neurovascular relationship subtypes for…
A Health Beliefs Model of Long-Term Prescription Opioid Use for Chronic Pain.
Although there is little evidence that very long-term (> 1 year) prescription opioid use is effective for non-cancer pain management, many patients continue prescription opioid use for many years. Interest in quitting and beliefs about opioid risks and benefits have not been measured i…
Ethological profiling defines pain behaviors and parses analgesia from drug side effects in a mouse model of complex regional pain syndrome.
Complex regional pain syndrome (CRPS) is a form of chronic postinjury pain affecting the extremities with contributions from the somatic and sympathetic nervous systems. The mouse tibial fracture-cast model was developed to enable preclinical study of CRPS mechanisms and guide condition-specific dru…
Sexually dimorphic roles of toll-like receptors in the central nervous system.
Many neurological and psychiatric diseases and disorders show sex differences in prevalence, incidence, disease manifestation and response to treatment. Yet, historically, most clinical and pre-clinical studies have been conducted disproportionately or exclusively in male subjects. In recent years,…
A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps.
The global coronavirus pandemic has led to a quiet wave of a chronic illness referred to as 'Long/Post Covid-19 syndrome' (LC) which bears a notable resemblance to functional-somatic or 'fibromyalgia-type' syndromes, and whose pathophysiology is undetermined. The lack of effective therapies for LC i…
Kinesiophobia, global health, pain, and bone mineral density in women with hypermobile Ehlers-Danlos syndrome: a prospective cohort study.
Hypermobile Ehlers-Danlos Syndrome (hEDS) is associated with joint hyperflexibility, pain, and connective tissue frailty. Patients are at high risk for fracture due to poor proprioception. This study reports on the mental and physical health, pain, physical activity, and kinesiophobia in patients wi…
An investigation of a novel public health campaign to improve understanding of persistent pain.
Persistent pain is a high priority global public health issue. Misconceptions about persistent pain prevail in society creating a culture towards pain that fosters stigma and non-evidence based, low value, management approaches. Thus, international groups have called for public health education init…
The Multifaceted Role of Social Media in Pain Medicine: Innovation, Education, Patient Engagement, and Challenges.
This article reviews the expanding role of social media in pain medicine, examining its impact on professional education, innovation dissemination, and patient engagement, with a focus on low back pain-related content and the need for training clinicians to evaluate online health content. Social med…