Ankylosing Spondylitis

Long-term functional and radiological outcomes among survivors of ankylosing spondylitis-associated cervical spine fractures: a cross-sectional follow-up study.

Patients with ankylosing spondylitis (AS) are predisposed to unstable cervical spine fractures, often following low-energy trauma. While short-term outcomes have been described, long-term functional and radiological outcomes among survivors remain poorly characterized. Survivor cohort study with com…

Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.

Ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) are 2 distinct spondyloarthropathies characterized by progressive spinal ankylosis. Despite their differing pathophysiologies, both conditions create long rigid spinal segments that are vulnerable to unstable fractures.…

Association between osteoporosis and arthritis: Results from the NHANES and Mendelian randomization study.

This study seeks to investigate associations of osteoporosis (OP) with arthritis and to assess causality using Mendelian randomization (MR). Firstly, an observational study was conducted using the National Health and Nutrition Examination Survey (NHANES). The relationship between OP and arthritis wa…

Cardiovascular risk goal attainment in the United States rheumatologic population.

Rheumatologic diseases are independently linked to premature cardiovascular (CV) events. The emerging field of cardio-rheumatology addresses the intersection of inflammation and accelerated atherosclerosis driving excess CV risk. Despite calls to action, data on risk factor optimization, antihyperli…

Instrument selection for the assessment of peripheral arthritis in axial and peripheral spondyloarthritis: an ASAS project.

To identify the most appropriate instrument to assess disease activity related to peripheral arthritis in axial spondyloarthritis (axSpA) and peripheral spondyloarthritis (pSpA) in clinical research. This Assessment of Spondyloarthritis International Society (ASAS) project followed the Outcome Measu…

Anti-TNF-induced vasculitis: analysis of data from the French national pharmacovigilance database.

The increasing use of tumor necrosis factor (TNF) inhibitors poses new challenges in terms of drug iatrogenicity and diagnosis. In this study, we focus on the description of the TNF-inhibitors-induced vasculitis. We conducted a retrospective descriptive study using the French national pharmacovigila…

Same Family, Different Stories: Distinct Peripheral Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis.

Viral metagenomic analysis of the blood virome in patients with multiple autoimmune diseases.

Autoimmune diseases are chronic and heterogeneous disorders resulting from the breakdown of immune tolerance and subsequent tissue damage. Beyond genetic predisposition, viral infections are increasingly recognized as pivotal environmental contributors to disease onset. In this study, we performed c…