Upregulation of serum circular RNA FUNDC1 and TNF-α in Behçet's disease: potential diagnostic biomarkers.
Behçet's disease (BD) is an inflammatory autoimmune disease characterized by relapsing genital ulcers, ocular involvement, and intestinal disorders. Evaluate serum levels of circular RNA (circRNA) FUNDC1 and tumor necrosis factor-alpha (TNF-α) in BD patients and compare them accordingly t…
Misdiagnosis of Behcet's disease lung involvement as pulmonary cryptococcosis on imaging: A case report.
Behçet's disease (BD) is a systemic vasculitis that rarely involves the lungs. Pulmonary manifestations of BD can radiographically mimic infectious pneumonia, posing a substantial diagnostic challenge and increasing the risk of inappropriate treatment. This case report describes a young female…
A Rare Presentation of Behçet's Disease: Coexistence of Intracardiac Thrombi, Coronary Artery Disease, and Pulmonary Thromboembolism.
Behçet's disease (BD) is a rare systemic vasculitis. While pulmonary involvement occurs, severe intracardiac manifestations are exceptional. We report a 44-year-old male presenting with dyspnea and hemoptysis. Multimodality imaging revealed bilateral pulmonary thromboembolism, severe three-vess…
Comorbid Inflammatory Diseases in Behçet's Disease: A Multicenter Large Cohort Study.
Behçet's disease (BD) is a chronic, multisystem immune-mediated vasculitis. A significant number of patients with BD have inflammatory comorbid (IC) disease that can affect the clinical course of the disease. In the current literature, there is no study which investigated IC disease in BD. It w…
Haploinsufficiency of A20 (HA20) is a primary immune regulation disease caused by heterozygous loss-of-function variants in TNFAIP3, resulting in unchecked inflammatory signaling. HA20 is a highly heterogeneous disorder with overlapping features of autoinflammation, autoimmunity, immunodeficiency, a…
Extension of cytokines' role in Behcet's disease associated peripheral neuropathy.
Behçet's disease (BD) is a chronic multisystem inflammatory disorder with diverse neurological manifestations. While central nervous system involvement is well recognized, peripheral neuropathy remains an underdiagnosed and poorly understood complication. Chemokines, particularly C-C motif chem…
Mapping Neuro Behcet's Disease Across North Africa: a Systematic Review and Meta Analysis.
Data on neuro-Behçet's disease in North Africa remain limited and fragmented. We conducted a systematic review and meta-analysis to estimate the frequency of neurologic involvement in North African patients with Behçet's disease and to summarize the main clinical, cerebrospinal fluid, and…