[Combined detection of urinary-related protein and fecal calprotectin for early warning of IgA vasculitis with nephritis in children].
To evaluate the early warning value of combined detection of urinary neutrophil gelatinase-associated lipocalin (NGAL), urinary microalbumin and fecal calprotectin for IgA vasculitis with nephritis (IgAVN). A total of 90 children with IgAV and 50 healthy children undergoing physical examination at Y…
[Pathological characteristics, therapeutic strategies, and prognostic assessment in children with crescentic IgA vasculitis with nephritis].
To analyze the associations between crescent proportion and renal pathology, laboratory indicators, and prognosis in children with IgA vasculitis with nephritis (IgAVN), and to assess the impact of different treatment strategies on urinary protein and prognosis. A total of 329 children with IgAVN an…
Granulomatosis with polyangiitis-associated choroiditis simulating serpiginous choroiditis.
To describe a rare presentation of bilateral choroiditis simulating serpiginous choroiditis as an initial ocular manifestation of granulomatosis with polyangiitis (GPA) and highlight clinical features that should prompt consideration of this diagnosis. A 73-year-old female with renal failure of unkn…
Engineering biomimetic coronary artery equivalents for Kawasaki disease modeling and drug screening.
Kawasaki disease (KD) is an acute vasculitis that primarily affects the pediatric population, with coronary artery lesions constituting its most severe clinical sequela. Although investigated for decades, the precise etiology and pathogenesis of this syndrome remain elusive. This critical knowledge…
Variability in Diagnosis and Treatment of Kawasaki Disease across the United States.
To analyze demographic characteristics, treatment, and outcome of patients with Kawasaki disease (KD), an acute vasculitis of children with unknown etiology, to gain insight into variation in care and epidemiologic clues regarding the etiology of KD. We analyzed the first admission of children diagn…
Early vascular lesion tracking in moyamoya disease: A case report with serial findings.
Moyamoya disease (MMD) is characterized by progressive stenosis of the internal carotid arteries and the presence of abnormal collateral vessels. However, knowledge of the early stages of MMD is limited. This case report discusses a woman in her 30s who experienced unusual symptoms, such as hand dys…
Immune regulatory mechanisms and potential microbiota-associated targets in Kawasaki disease: an integrative multi-omics and network pharmacology study.
Kawasaki disease (KD) is a systemic vasculitis in children primarily affecting the coronary arteries, and studies suggest that the gut microbiota may be involved in KD pathogenesis, inflammatory responses, and immune regulation. This study employed an integrative multi-omics strategy to systematical…