Cost-effectiveness of perioperative pembrolizumab plus enfortumab vedotin for cisplatin-ineligible or cisplatin-declining patients with muscle-invasive bladder cancer in the United States.
In the KEYNOTE 905/EV 303 study, perioperative enfortumab vedotin plus pembrolizumab (EV+Pem) improved event-free survival (EFS), overall survival (OS), and pathological complete response in a predominantly cisplatin-ineligible muscle-invasive bladder cancer (MIBC) population, compared with surgery…
Multimodal approach to identify neuropsychophysiological subgroups in myalgic encephalomyelitis/chronic fatigue syndrome and their relevance for rehabilitation: protocol for a mechanistic cross-sectional and longitudinal study.
Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) is a debilitating condition characterized by severe fatigue and post-exertional malaise (PEM). Reported neuropsychophysiological abnormalities suggest ME/CFS is multifactorial, but current knowledge remains fragmented. This study protocol…
Exploring differences in protein cargo of extracellular vesicles from ME/CFS patient plasma compared to healthy controls.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease characterized by post-exertional malaise, fatigue and pain. Yet, its underlying biological mechanisms remain poorly understood. Extracellular vesicles (EVs) are nanoparticles carrying biological cargo a…
Synergistic backbone-side chain design via noncovalent interactions for advanced high-temperature proton exchange membranes.
High-temperature proton exchange membrane (HT-PEM) fuel cells are essential for efficient hydrogen energy conversion, yet their performance is often limited by insufficient proton transport and poor phosphoric acid (PA) retention of HT-PEMs. Current strategies mainly rely on covalent structural modi…
Identifying EEG biomarkers of fatigue and brain fog in long COVID: insights from rest and movement-related brain activity.
Fatigue and brain fog are among the most reported symptoms in Long COVID (LC), yet their underlying neural mechanisms remain unclear. In this context, we aimed to identify neural correlates associated with LC symptoms. Electroencephalography (EEG) was used to quantify brain oscillatory activity duri…
[Research progress on acupuncture and moxibustion in regulating mitochondrial function for chronic fatigue syndrome].
Chronic fatigue syndrome (CFS) is a neurological disorder primarily characterized by persistent fatigue, post-exertional malaise, and cognitive dysfunction. Mitochondrial dysfunction is considered as a core mechanism underlying its pathological changes. Acupuncture and moxibustion therapy has been s…
Synthesize High Efficiency CuO/Mullite Catalysts for Methanol Steam Reforming to Produce Hydrogen: On the SMSI Effect Originating from the Strong CuO-Support Interaction.
Methanol steam reforming (MSR) is a promising and potential technology to supply H2 for on-board power systems utilizing proton exchange membrane (PEM) fuel cells. Developing high-performance catalysts at low temperature is still a great challenge. Herein, CuO-supported on different AMn2O5 mullites…
Prospective Detection of Hypoglycemia and Near-Hypoglycemia Inducing Pressure-Induced Sensor Attenuation Onset in Continuous Glucose Monitoring Time Series.
Continuous glucose monitoring (CGM) sensors are vulnerable to pressure-induced sensor attenuations (PISAs). Pressure-induced sensor attenuations are characterized by a rapid but erroneous drop in blood glucose (BG) readings, and if these BG readings are hypoglycemic or near-hypoglycemic they can cau…