Altered Interoceptive Predictive Coding in Functional Neurological Disorders.
Interoception, the processing of internal bodily signals, has been linked to the pathophysiology of Functional Neurological Disorder (FND), along with the theoretical concept of altered predictive coding (PC). FND symptoms such as sensory-motor dysfunction may arise from disrupted integration of sen…
Conceptual Overlap Between OPTIMAL Theory Constructs and Motor Presentations in Functional Neurological Disorder Rehabilitation.
Functional neurological disorder (FND) is increasingly recognized as a disorder of brain network dysfunction with neuroimaging studies demonstrating altered communication among neural circuits involved in movement, attention, and self-agency. The Optimizing Performance Through Intrinsic Motivation a…
Prognostic Significance of Early Fever in Convulsive Status Epilepticus: Insights from the ICTAL Registry.
Fever is one of the secondary brain insults that may alter outcome after acute brain injury. However, its deleterious role in convulsive status epilepticus (CSE) remains insufficiently established in humans. We aimed to determine whether early fever is associated with functional neurological outcome…
Clinical characteristics and semiological pitfalls in patients with focal epilepsy and functional/dissociative seizures: A comparative analysis of correct and incorrect initial diagnoses.
Both epilepsy and functional/dissociative seizures (FDS) can present with a wide variety of event manifestations which can appear similar in nature and contribute to misdiagnosis. Whereas many studies have addressed the misdiagnosis of FDS as epilepsy, research into the inverse, where epilepsy is mi…
Coexisting Postural Orthostatic Tachycardia Syndrome on Autonomic Reflex Testing in Functional Neurologic Disorder.
BACKGROUND Functional neurological disorder (FND) is characterized by neurological symptoms identified through positive clinical signs that are incongruent with recognized structural neurological disease. Postural orthostatic tachycardia syndrome (POTS), in contrast, is defined by excessive orthosta…
Functional Neurological Symptom Disorder Obscured by Incomplete Diagnostic Communication: A Case Report.
Functional neurological disorder (FND) is a diagnosis grounded in positive clinical signs, yet it remains vulnerable to underdocumentation and incomplete communication across care transitions, particularly when it is suspected but not formally recorded. In this case, a 24-year-old woman with a histo…
Unmet needs in functional neurological disorder related to digital healthcare.
Functional neurological disorder (FND) is a common yet historically neglected condition that presents major unmet needs across diagnosis, treatment and health service delivery. This article examines how digital healthcare could address gaps in several areas: (i) using large biobank and clinic datase…
Patients' perspectives of navigating support following a diagnosis of functional neurological disorder: an interpretive phenomenological study.
Currently in the United Kingdom, service provision for functional neurological disorder (FND) varies greatly, while research has suggested difficult experiences of receiving care by those diagnosed with FND. To improve understanding of the needs of this client group, this research aimed to explore t…