What helps? Patient-reported strategies for managing functional/dissociative seizures: a cross-sectional survey.
The value of incorporating lived experience into research is increasingly recognised, however, traditional functional/dissociative seizure (FDS) treatment studies assess treatment efficacy prior to ascertaining real-world effectiveness. This study aimed to gather firsthand accounts from individuals…
Identifying unique gait phenotypes across neuromotor conditions using wearable inertial sensors and topological data analysis.
Wearable sensors quantify gait and mobility in detail, but translating high-dimensional data into clinically actionable insights remains challenging in precision rehabilitation. We applied Topological Data Analysis (TDA) to inertial sensor recordings from multiple gait assessments in 81 individuals…
[Clinical management of headache comorbid with functional neurological disorder].
Headache, particularly migraine, is highly prevalent in patients with functional neurological disorder (FND) but is often underrecognized in clinical practice. This review provides an overview of the existing literature on the association between FND and headache and demonstrates that comorbid migra…
Dynamics of the systemic inflammatory response surrounding stressors and the association with neuropsychiatric and somatic outcomes.
Acute and chronic stressors contribute to neuropsychiatric disorders. However, the role of inflammatory dynamics around stress exposure remains unclear. Using TriNetX, an international electronic health records database, we examined how systemic inflammatory activity and its temporal dynamics relate…
Too Complex to Treat? Equity in Access to Inpatient Pediatric Pain Rehabilitation.
An adolescent with complex regional pain syndrome, functional neurological symptoms, and significant psychosocial complexity was hospitalized for severe decline. Despite meaningful progress through a structured, multidisciplinary inpatient approach, she was repeatedly denied admission to pediatric i…
We created fictional case scenarios that might be managed either in primary or secondary care to compare the approaches of a general practitioner, a neurology trainee and a consultant neurologist. Overall, we found them to be similar, with a preference for an approach of 'ruling out worst-case scena…
Diagnostic Agreement and 1-Year Outcomes in Functional Neurological Disorder Following Neuroscience-Informed Assessment, Education, and Counseling: A Retrospective Cohort Study.
We sought to explore outcomes at 1 year in functional neurological disorder (FND) following a neuroscience-informed education and counseling assessment. Patients with FND were assessed at a quaternary neuropsychiatry clinic in Toronto, Canada, and provided education and counseling to build insi…
Neuropsychological assessment of tetanus anaphylactic shock and medical trauma.
Tetanus anaphylactic shock can be life-threatening, yet no studies have examined its short- or long-term neuropsychological and psychological effects. Whether cognitive and psychological symptoms follow tetanus allergic reactions remains unknown. This is the first case report presenting two neuropsy…
mscervical instabilityfunctional neurologicalbrain fog