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Interstitial Cystitis

108 papers & discussions

A chronic bladder condition causing pelvic pain, urinary urgency, and frequency without infection.

Pelvic painUrinary urgencyUrinary frequencyBladder pressureFatiguePain with intercourse

Research

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PubMed

Real-world all-cause healthcare resource utilization and costs among patients with interstitial cystitis/bladder pain syndrome in the United States.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a persistent and heterogeneous condition diagnosed by exclusion, defined by a bladder-associated unpleasant sensation (e.g. pain, pressure, or discomfort), and affecting patients' quality of life. This real-world study aimed to describe all-cau…

chronic paininterstitial cystitis
PubMed

Nanoparticle-based therapeutic platforms for inflammatory disorders of the urinary system: Engineering local delivery, biointerface regulation, and smart responsive therapy.

Inflammatory diseases of the urinary system, including urinary tract infection (UTI), catheter-associated urinary tract infection (CAUTI), interstitial cystitis/bladder pain syndrome (IC/BPS), and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), are associated with high recurrence, comple…

chronic paininterstitial cystitispelvic pain
PubMed

A pilot study of a urinary IL-8 and IL-17-based formula for discriminating Hunner-type from non-Hunner-type interstitial cystitis.

To determine whether urinary or plasma cytokines more effectively differentiate Hunner-type interstitial cystitis (HIC) from non-Hunner-type interstitial cystitis (NHIC), and to develop an interpretable discriminative formula based on the most informative features. Paired urine and plasma samples we…

interstitial cystitis
PubMed

Corrigendum to "Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis" [Mater. Today Bio 38 (2026) 103112].

[This corrects the article DOI: 10.1016/j.mtbio.2026.103112.].

interstitial cystitis
PubMed

Urinary Biomarkers in Interstitial Cystitis and Bladder Pain Syndrome: A Narrative Review of Differential Diagnosis and Treatment Monitoring.

The objective was to narratively synthesize clinical studies of urinary biomarkers in interstitial cystitis/bladder pain syndrome (IC/BPS) and evaluate their utility for differential diagnosis versus overactive bladder (OAB), pre-cystoscopy biomarker enrichment for Hunner-lesion IC (HIC), and monito…

chronic paininterstitial cystitis
PubMed

Multiclass Diagnostic Improvement of Interstitial Cystitis (IC) and Overactive Bladder (OAB) via Machine Learning Pipeline on Surface-Enhanced Raman Spectroscopy (SERS).

Interstitial cystitis (IC) and overactive bladder (OAB) are chronic pelvic conditions with shared symptoms of urinary urgency, increased frequency, and nocturia with pain in the bladder. IC is characterized by bladder pain and inflammation without a clear etiology, whereas OAB involves detrusor over…

interstitial cystitis
PubMed

Pentosan polysulfate sodium and retinal safety: reconciling conflicting evidence and defining a pragmatic clinical pharmacology framework.

Pentosan polysulfate sodium (PPS) remains an oral treatment option for selected patients with bladder pain syndrome, but recognition of PPS-associated pigmentary maculopathy has created uncertainty about long-term prescribing. The central clinical problem is that reported retinal-risk estimates vary…

chronic paininterstitial cystitis
PubMed

Clinical efficacy of bladder hydrodistension combined with oral mirabegron and intravesical instillation in the treatment of interstitial cystitis.

To evaluate the therapeutic efficacy of bladder hydrodistension combined with oral mirabegron and intravesical instillation in patients with interstitial cystitis(IC). This was a retrospective study. Ninety patients diagnosed with IC at The Second Hospital of Hebei Medical University between October…

interstitial cystitis

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