Interstitial Cystitis

Real-world all-cause healthcare resource utilization and costs among patients with interstitial cystitis/bladder pain syndrome in the United States.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a persistent and heterogeneous condition diagnosed by exclusion, defined by a bladder-associated unpleasant sensation (e.g. pain, pressure, or discomfort), and affecting patients' quality of life. This real-world study aimed to describe all-cau…

Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances in symptomatic management, CP…

Interstitial Cystitis/Bladder Pain Syndrome: A Narrative Review of Nomenclature, Epidemiology, Pathophysiology, Diagnosis, and Management.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a long-term condition characterized by bladder pain, pressure, or discomfort, combined with urinary urgency and frequency, without any other identifiable cause. Despite many years of research, its origins are not fully known, and there is still…

Treatment of interstitial cystitis with intravesical instillation of recombinant human collagen type Ⅲ.

Interstitial cystitis (IC) is a chronic condition characterized by frequent urination, urgency, and pelvic pain. While its pathogenesis remains incompletely understood, the prevailing epithelial theory suggests that a defective glycosaminoglycan (GAG) layer increases bladder permeability, allowing u…

Mesenchymal stem Cells and Extracellular Vesicles in Bladder Dysfunction: Mechanisms and Translational Perspectives.

Bladder dysfunction comprises diverse lower urinary tract disorders lacking treatments that restore tissue integrity and neural control. While mesenchymal stem cells (MSCs) show promise in regenerative urology, their benefits primarily stem from paracrine mechanisms. Consequently, MSC-derived extrac…

ERN ReCONNET-SLICC-SLEuro consensus on the therapeutic management of rare systemic lupus erythematosus manifestations (part 2).

Systemic lupus erythematosus (SLE) guidelines predominantly focus on common major organ involvement. An international taskforce from three SLE expert groups (European Reference Network on Connective Tissue and Musculoskeletal Diseases, Systemic Lupus International Collaborating Clinics, and the Euro…

Challenges in modeling interstitial cystitis: implications for drug discovery efforts.

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by bladder pain and lower urinary tract symptoms. Despite extensive investigation and numerous therapeutic candidates, few disease-modifying treatments have translated into clinical practice. Evidence indicates…

Corrigendum to "Diagnosis of interstitial cystitis/bladder pain syndrome: Guidelines from the Committee of Female Urology (CUROPF) of the French Association of Urology (AFU)" [The French Journal of Urology 36 (2026) 103166].