Development and Preliminary Clinical Evaluation of a Multifunctional Operative Support Arm in Reproductive Laparoscopic Surgery: A Randomized Controlled Study.
To evaluate short-term clinical outcomes, surgeon-reported fatigue, and staff user experience associated with a multifunctional operative support arm in reproductive laparoscopic surgery. Single-center, parallel-group randomized controlled trial. Tertiary university-affiliated reproductive medicine…
A woman's worth: Self-compassion as a mediator between optimism and beliefs about motherhood, identity, and infertility of women with endometriosis.
The aim of the present study was to analyze the mediating role of self-compassion between trait optimism and beliefs about woman identity, motherhood and infertility among women with endometriosis, adjusting for endometriosis stage and operation status. The participants were 139 women diagnosed with…
MGST3 Promotes Endometriosis Progression by Suppressing Ferroptosis.
Endometriosis (EMs) is characterized by dysregulated persistence and enhanced invasiveness of ectopic endometrial cells. Current treatment strategies remain limited by high recurrence rates and considerable adverse effects. Although iron overload is a recognized feature of EMs, ectopic lesions parad…
Deep immune profiling of endometrial and peripheral blood cells in endometriosis.
How is endometrial and systemic immunity modulated throughout the menstrual cycle and are there changes in women with endometriosis? Endometriosis is associated with reduced endometrial early natural killer (NK) cells and increased mucosal-associated invariant T (MAIT)-like CD8+ T cells, with cyclic…
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis.
Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting pathogenic signals through bacterial extracellular vesicles (BEVs).…
Initial Results of FAPI PET/MRI to Assess the Extent of Endometriosis.
Endometriosis is a common gynecologic disorder often associated with chronic pelvic pain, infertility, and reduced quality of life. Conventional imaging modalities, such as transvaginal ultrasound and MRI, may underestimate the extent of disease, particularly in deep infiltrating endometriosis. Fibr…
Gut-reproduction axis: genome-wide pleiotropic and prospective evidence linking inflammatory bowel disease with gynecological disorders.
We aimed to explore shared genetic architectures and potential causal associations between inflammatory bowel disease (IBD) and gynecological diseases, including ovarian cysts (OC), pelvic inflammatory disease (PID), and endometriosis (EMs), and to evaluate whether the findings are consistent with a…