Association between psychological wellbeing and the COVID-19-related outcomes in Europeans aged ≥ 50 years old: The SHARE study.
The aim of the present study was to prospectively investigate the associations between psychological wellbeing and COVID-19 outcomes (vaccination, infection, long COVID) based on the Survey of Health, Aging, and Retirement in Europe (SHARE), using the data from Wave 8 and two supplementary COVID-19…
Ozone therapy by rectal insufflation in long COVID syndrome: a preliminary study with thermographic evaluation and quality of life measurement.
Post-acute coronavirus disease 2019 syndrome (PACS) is a multisystemic clinical condition that clinically starting weeks or even months after acute SARS-CoV-2 (COVID 19) infections. The objective of this study was to explore change in quality of life, mechanical force and metabolic activity after oz…
Evaluation of nirmatrelvir/ritonavir treatment for COVID-19 on health-related outcomes: a global economic value systematic literature review.
Nirmatrelvir/ritonavir (NMV/r)i is an antiviral drug indicated for the treatment of patients with mild to moderate coronavirus disease 2019 (COVID-19) who are at high risk of progressing to severe disease. We performed an updated economic systematic literature review (eSLR) of NMV/r to build upon ev…
Gut microbiome signatures during acute infection are associated with long COVID.
Long COVID (LC) manifests in 10%-30% of non-hospitalized individuals post-SARS-CoV-2 infection, leading to significant morbidity. The predictive role of gut microbiome composition during acute infection in the development of LC is not well understood, partly because of the heterogeneous nature of th…
Recovery trajectories and predictors of symptom resolution in post-COVID-19 condition: a population-based cohort study.
SARS-CoV-2 infection can lead to persistent symptoms, known as Post-COVID-19 Condition (PCC). Previous studies on PCC prognosis mainly looked at severe cases in rehabilitation settings and without knowledge about pre-infection symptom levels. Uncertainty remains about recovery trajectory in the gene…
Central sensitization in long COVID: Associations with autonomic symptom burden, cerebral hypoperfusion, and neuroinflammation.
The mechanisms driving the broad spectrum of Long COVID symptoms-such as fatigue, brain fog, pain, and dysautonomia-remain uncertain. This study investigated central sensitization (CS) as a potential contributor to symptom burden in patients with Long COVID. We aimed to examine its association with…
Glucose metabolism across COVID-19 and long COVID: a longitudinal study.
COVID-19 has been associated with new-onset diabetes. Prior studies are limited by lack of pre-infection data and preexisting cardiometabolic factors. Clarifying how COVID-19 and long COVID (LC) affect glucose metabolism is essential to guide prevention. We evaluated longitudinal changes in glycemic…
Long COVID symptom profiles, workforce participation, and working hours among adults in England: a population-based cohort study.
Long COVID, marked by ongoing multi-systemic symptoms following COVID-19 infection, can impair ability to maintain employment. However, its relationship to workforce retention and working hours remains unclear. Long COVID was defined as symptoms lasting ≥12 weeks post-infection. We analysed d…