Evaluation of nirmatrelvir/ritonavir treatment for COVID-19 on health-related outcomes: a global economic value systematic literature review.
Nirmatrelvir/ritonavir (NMV/r)i is an antiviral drug indicated for the treatment of patients with mild to moderate coronavirus disease 2019 (COVID-19) who are at high risk of progressing to severe disease. We performed an updated economic systematic literature review (eSLR) of NMV/r to build upon ev…
Pandemic research in a small island society-a narrative review of research contributions during the SARS-CoV-2 pandemic in the Faroe Islands.
Small and geographically isolated societies face distinct challenges during a pandemic but may also possess advantages. This narrative literature review presents epidemiological, immunological and psychological studies conducted in the Faroe Islands during the SARS-CoV-2 pandemic, examining its effe…
Association between psychological wellbeing and the COVID-19-related outcomes in Europeans aged ≥ 50 years old: The SHARE study.
The aim of the present study was to prospectively investigate the associations between psychological wellbeing and COVID-19 outcomes (vaccination, infection, long COVID) based on the Survey of Health, Aging, and Retirement in Europe (SHARE), using the data from Wave 8 and two supplementary COVID-19…
Ozone therapy by rectal insufflation in long COVID syndrome: a preliminary study with thermographic evaluation and quality of life measurement.
Post-acute coronavirus disease 2019 syndrome (PACS) is a multisystemic clinical condition that clinically starting weeks or even months after acute SARS-CoV-2 (COVID 19) infections. The objective of this study was to explore change in quality of life, mechanical force and metabolic activity after oz…
Gut microbiome signatures during acute infection are associated with long COVID.
Long COVID (LC) manifests in 10%-30% of non-hospitalized individuals post-SARS-CoV-2 infection, leading to significant morbidity. The predictive role of gut microbiome composition during acute infection in the development of LC is not well understood, partly because of the heterogeneous nature of th…
Hair cortisol concentration and basal heart rate variability differentiate long COVID from depressive disorders in youth.
Depressive symptoms are highly prevalent in long COVID (LC) and may shape its symptom burden. As hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system (ANS) alterations have been implicated in both LC and depressive disorders, this overlap raises the question of whether both conditi…
Associations between subjective cognitive difficulties, cognitive test performance, psychiatric symptoms, and quality of life in pediatric long COVID.
Objective: This retrospective study examined the associations between subjective cognitive difficulties, performance scores on standardized cognitive tests, and quality of life (QoL) among pediatric patients with long COVID. Method: This study included 82 pediatric patients with long COVID referred…
Long-COVID Associated With Incident Hypertension: A Population-Based Cohort Study.
Long COVID has been linked to persistent autonomic and vascular abnormalities, but its impact on hypertension among non-hospitalized COVID-19 convalescents remains unclear. Given the link between blood pressure and cardiovascular morbidity, understanding how long COVID modifies the risk of incident…