Neuromyelitis Optica

Complement C3 inhibitory peptide AMY-101 ameliorates brain injury in a mouse model of NMOSD.

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system, clinically characterized primarily by optic neuritis and transverse myelitis. This study aimed to investigate the therapeutic potential of the complement C3 inhibitory pe…

Fixation techniques for the Levonorgestrel-Releasing Intrauterine system in adenomyosis: a narrative review.

Adenomyosis causes severe dysmenorrhoea and menorrhagia. While the Levonorgestrel-Releasing Intrauterine System (LNG-IUS) is a highly effective conservative treatment, its success is frequently compromised by high expulsion rates (15%-37.5%) caused by uterine enlargement and cavity distortion. This…

Statement of Retraction: The role of autophagy-related proteins in the pathogenesis of neuromyelitis optica spectrum disorders.

Human factors validation study of a disposable autoinjector (Bmab 1200 autoinjector) for subcutaneous delivery of Ustekinumab.

Ustekinumab is approved for treating moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. The Bmab 1200 autoinjector is a simple, two-step device for subcutaneous ustekinumab biosimilar delivery. This was an in vitro, nonclinical, simulated-use human fac…

Development and Preliminary Clinical Evaluation of a Multifunctional Operative Support Arm in Reproductive Laparoscopic Surgery: A Randomized Controlled Study.

To evaluate short-term clinical outcomes, surgeon-reported fatigue, and staff user experience associated with a multifunctional operative support arm in reproductive laparoscopic surgery. Single-center, parallel-group randomized controlled trial. Tertiary university-affiliated reproductive medicine…

Commensal microbiota-coated biohybrid implants induce antibiofilm, osteogenic, and immunomodulatory responses in a human 3D immunocompetent model.

Medical devices have revolutionized patient care; however, their abiotic surfaces remain highly susceptible to bacterial biofilm formation, enabling immune evasion and antibiotic resistance. Although antibacterial coatings can mitigate bacterial colonization, many rely on antimicrobial agents that m…

Characterization of visceral branch geometry in a four-branch off-the-shelf device for endovascular repair of paravisceral and thoracoabdominal aortic aneurysms.

This study aims to evaluate visceral branch geometry, including angulation, tortuosity, and diameter, of the GORE EXCLUDER thoracoabdominal branch endoprosthesis (TAMBE) in real-world utilization. All patients were identified and treated with TAMBE from June 2024 to June 2025 at a single institution…

Neuromyelitis optica presenting with mammillary body and cervicomedullary lesions after severe hyponatremia mimicking osmotic demyelination syndrome.

Neuromyelitis optica spectrum disorder is an autoimmune demyelinating disease that usually targets the spinal cord and optic nerves, though occasionally other central nervous system structures are involved. There are variants of neuromyelitis optica spectrum disorder that can mimic metabolic or osmo…