Reduction of Cerebrospinal Fluid Leaks in Idiopathic Intracranial Hypertension with Glucagon-like Peptide-1 Receptor Agonist Use.
Elevated intracranial pressure (ICP) secondary to idiopathic intracranial hypertension (IIH) is a recognized risk factor for anterior and lateral skull base cerebrospinal fluid (CSF) leaks. A recent randomized controlled trial (Mitchell et al) demonstrated a significant reduction of ICP in IIH with…
Potential role of tirzepatide, a dual GLP-1 and GIP receptor agonist, for preventive treatment of migraine: A case series.
Obesity is a known comorbidity of migraine that can increase attack frequency and severity and lead to disease chronification. Glucagon-like peptide-1 (GLP-1) receptor agonists and related medications have demonstrated benefits beyond glycemic control and weight management, with emerging evidence su…
The Clinical Characteristics and Laboratory Findings of Early and Late Onset Pediatric Idiopathic Intracranial Hypertension: A Single-Centre Experience.
The objection of the study was to evaluate the features of pediatric idiopathic intracranial hypertension (IIH) at different age groups. This prospective study was done in Pediatric Neurology Department, National Institute of Neurosciences and Hospital, Bangladesh from January 2018 to June 2020. Tot…
Identifying MicroRNA Biomarkers in Idiopathic Intracranial Hypertension: A Pilot Study.
Idiopathic intracranial hypertension (IIH) is characterized by raised intracranial pressure (ICP). It predominantly affects women with obesity and can cause disabling headaches and permanent visual loss. IIH is misdiagnosed in up to 40% of cases. Diagnosis and monitoring often rely on frequent invas…
The Lumboperitoneal Shunt Study: A Systematic Review and Single-Arm Meta-Analysis of 2696 Patients.
Lumboperitoneal shunt (LPS) is often regarded as a secondary treatment option for various forms of hydrocephalus. While some studies have compared its results to conventional treatments, there needs to be more comprehensive evidence systematically evaluating its isolated outcomes. The authors system…
Intensive Care Unit Management of Meningitis and Encephalitis.
Meningitis and encephalitis are neurologic emergencies that require rapid recognition and treatment. Prompt diagnosis and administration of antimicrobials, alongside adjuvant steroids in select cases, are crucial for treatment and improvement in outcomes. Severe complications of meningitis and encep…
Recurrent crescendo headache and subconjunctival hemorrhage in the setting of intracranial hypertension with IgA nephropathy.
This case report presents the diagnostic complexity and longitudinal management of a 39-year-old woman with progressive headaches found to have idiopathic intracranial hypertension with an atypical presentation of recurrent unilateral subconjunctival hemorrhages and a reported association with IgA n…