Clinical and genetic association of comorbid provisional PMDD and ADHD in female patients with bipolar disorder.
Premenstrual dysphoric disorder (PMDD) is a common comorbidity in bipolar disorder (BD), and its association with severe illness course and other comorbidity in BD has been reported. This study aims to investigate clinical characteristics and polygenic risk features of the subgroup with DSM-5-based…
A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed-loop system.
In type 1 diabetes (T1D), insulin requirements and glycemic control may vary across the menstrual cycle. We examined phase-related differences in insulin requirements, glycemic metrics, and recorded carbohydrate amounts in women using an advanced hybrid closed-loop (AHCL) system and their associatio…
Premenstrual Dysphoric Disorder Severity and Associated Factors Among Female College Students in Nekemte Town: An Institution-Based Cross-Sectional Study.
Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome characterized by marked affective, behavioral, and physical symptoms that occur during the late luteal phase of the menstrual cycle and substantially impair daily functioning. Despite its considerable impact on the heal…
Menstrual cyclicity of cannabis use: a longitudinal study using phase-aligned cycle time scaling (PACTS).
Despite rising rates of cannabis use and cannabis use disorder (CUD) among females, research on female-specific implicated factors remains limited. Emerging evidence suggests that substance use behavior may fluctuate across the menstrual cycle, particularly among individuals with premenstrual disord…
Premenstrual Disorders in Adolescents: An Interdisciplinary Perspective.
Background: Premenstrual disorders (PMDs), including premenstrual syndrome and premenstrual dysphoric disorder, are common conditions that may substantially affect adolescents' physical and psychological well-being. However, their presentation and management during adolescence are complicated by rep…
RORA as a sex-specific molecular link in autism spectrum disorder: from transcriptional regulation to clinical phenotype across the lifespan.
RORA is a molecular hub in autism spectrum disorder (ASD) that integrate sex steroid signaling, neurodevelopmental gene regulation, circadian rhythm, immune function and metabolic homeostasis. Convergent evidence from postmortem brain, peripheral blood, methylation profiling, animal models and cellu…
Impact of women's coping with premenstrual symptoms on dyadic adjustment and perceived social support: a cross-sectional study in Turkey.
To investigate the impact of women's coping with premenstrual symptoms on dyadic adjustment and perceived social support. The study was conducted with a descriptive and cross-sectional design between October 2023 and February 2024. The following instruments were administered online: the personal inf…
Psychobiological stress and premenstrual symptoms across the menstrual cycle: protocol for an ecological momentary assessment (ISSAC) study.
Premenstrual symptoms occur on a continuum from mild experiences to clinically significant, menstrual cycle-related mood disorders, including premenstrual dysphoric disorder (PMDD). Stress has been implicated as a key pathophysiological factor, yet the temporal coupling and dynamics between psychobi…