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Primary Sclerosing Cholangitis

392 papers & discussions

PSC is a rare liver disease causing chronic inflammation and scarring of the bile ducts.

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Research

392
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PubMed

Examining Cost Differences in Malignant Brain and Central Nervous System Tumor Treatment Across US Military Health System Care Settings.

The objectives of this study were to determine whether the cost of care for malignant brain and other central nervous system tumors (MBT) in the US Military Health System differs between the Department of War-operated direct care (DC) network and the affiliated civilian-operated private sector care…

psc
PubMed

Electroacupuncture modulates cortical functional connectivity and network topology in healthy adults: an fNIRS study.

Acupuncture has shown clinical benefits in post-stroke rehabilitation, yet its central neural mechanisms remain incompletely understood. In particular, how cortical activation, inter-regional functional connectivity, and brain network topology are modulated during electroacupuncture stimulation has…

psc
PubMed

Design methodology for a photovoltaic emulator based on power hardware-in-the-loop with Opal-RT simulator.

This study introduces a design methodology for a photovoltaic (PV) power emulator system. The proposed framework establishes a simple and rapid approach to constructing a PV emulator by utilizing a real-time simulator to control a power amplifier supply, forcing it to mimic the operational character…

psc
PubMed

Environmental shaping of tolerance failure in autoimmune liver diseases: a phenotype-specific framework with primary biliary cholangitis as the strongest model.

Autoimmune liver diseases (primary biliary cholangitis, PBC; primary sclerosing cholangitis, PSC; autoimmune hepatitis, AIH) are three distinct, organ-specific autoimmune disorders that share loss of tolerance as the central pathophysiological mechanism but differ in target tissue, age of onset, gen…

psc
PubMed

Exploring burnout: An online survey among diverse nursing teams in Germany.

Immigration and the increasing shift toward nursing as a university degree lead to greater diversity in German nursing teams and have an impact on cooperation in everyday nursing care. Studies on the interactions between psychosocial working conditions and individual diversity characteristics on the…

psc
PubMed

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo-immunotherapy: A case report.

Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of non-small-cell lung cancer, characterized by high invasiveness and treatment resistance. Patients with PSC often exhibit poor treatment outcomes, short median survival and a dismal prognosis, necessitating novel comprehensive treatment strat…

psc
PubMed

PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis.

Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease-specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertai…

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PubMed

The Gut-Liver Immune Axis in Celiac Disease, Primary Sclerosing Cholangitis, and Ulcerative Colitis: Outcomes of a Rare but Significant Triad.

Purpose To characterize the clinical presentation, disease course, and outcomes of patients with concurrent primary sclerosing cholangitis (PSC) and celiac disease (CeD), including those with concomitant inflammatory bowel disease (IBD). Methods Retrospective EHR analysis (MGB RPDR, BIDMC Celiac Cen…

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