[Neural mechanism of acupuncture-driven vagus nerve-gastric reflex regulating gastric motility in mice with diabetic gastroparesis].
To observe the immediate regulatory effect of electroacupuncture (EA) on gastric motility via the vagus nerve in mice with diabetic gastroparesis (DGP), and to explore the potential central mechanism related to vagus nerve underlying the effects of acupoints. A total of 27 male C57BL/6 mice of clean…
Hypermucinous Dysplasia in Inflammatory Bowel Disease (IBD): Morphology, Molecular Features, and Its Place in the IBD-Associated Neoplastic Spectrum.
Long-standing inflammatory bowel disease (IBD) increases the risk of dysplasia and colorectal cancer (CRC), particularly in patients with extensive disease or coexisting primary sclerosing cholangitis (PSC). Several non-conventional dysplasia subtypes have been identified. Hypermucinous dysplasia wa…
Real-world efficacy and safety of immune checkpoint blockades in advanced urothelial carcinoma with histologic variant subtypes: the pembroblad study.
Histologic variants (HV) of urothelial carcinoma (UC-V) and non-urothelial carcinomas (NUC) of the bladder and urinary tract are aggressive malignancies with poor prognosis and limited response to platinum-based chemotherapy. Despite their biological particularities and distinct immune microenvironm…
Personalized barrier recovery induced by Lactobacillus helveticus SBT2171 in an In Vitro model of ulcerative colitis-derived fecal supernatants.
Disruption of the intestinal epithelial barrier is a hallmark of inflammatory bowel disease (IBD). Although probiotics and postbiotics are increasingly recognized as potential therapeutic approaches, treatment efficacy is often influenced by patient-specific variability. In this study, intestinal in…
Tele-triage, care substitution, and health: Evidence from quasi-randomly assigned nurses.
Patients experiencing acute health symptoms often face uncertainty about how and where to receive care. We study patients who call a nurse advice line and receive one of four recommendations: emergency department (ED), urgent care (UC), primary care (PC), or self-care (Home). Leveraging an extension…
The clinical utility of telangiectasia quantification as markers of vascular disease progression in systemic sclerosis.
Telangiectasia are common in systemic sclerosis (SSc). We explored the relationship between the site and quantity of telangiectasia with disease characteristics in SSc and the agreement between patient and physician-reported quantification of telangiectasia. A retrospective analysis of a large, cros…
Lacrimal gland ultrasonography as an adjunct tool for Sjögren disease (SjD) diagnosis from undifferentiated connective tissue diseases.
Sjögren disease (SjD) is characterized by autoimmune lymphocytic infiltration of lacrimal and salivary glands, leading to dry eye and dry mouth. This study aimed to investigate the features and diagnostic value of lacrimal gland ultrasonography (LGUS) for distinguishing SjD from undifferentiate…
Serum and Urine Nerve Growth Factor and Glycosaminoglycan Levels in Obstructive and Non-Obstructive Feline Urolithiasis and Interstitial Cystitis.
Feline interstitial cystitis (FIC) results from complex interactions between the urinary bladder, nervous system, adrenal glands and the cat's living environment. Following FIC, urolithiasis is the second most common cause of feline lower urinary tract disease (FLUTD), often producing clinical signs…