Interface Between Ophthalmology and Rheumatology in Uveitis and Retinal Vasculitis in Adult Patients, When Does Who Need Whom?
BACKGROUND: There is a significant interface between ophthalmology and rheumatology, particularly in uveitis and retinal vasculitis. This will be described in detail here. RESULTS: Analyses of uveitis consultations from university centres in Austria and Germany show that approximately 30% of anterio…
Sarcoidosis is a multisystem granulomatous disease that commonly affects the lungs and intrathoracic lymph nodes. On imaging, characteristic patterns of lymphadenopathy, such as the lambda sign on fluorodeoxyglucose positron emission tomography (FDG PET), are considered suggestive of the disease and…
Saliva as a Non-Invasive Diagnostic for Ocular Sarcoidosis.
Sarcoidosis (SRS) is a multi-organ granulomatous disorder that predominantly affects the eyes, lungs, and skin. Biopsy, the standard for a definitive SRS diagnosis, is often impractical for ocular sarcoidosis (OSRS) due to the delicate nature of the eye and risks associated with surgical procedures…
Histopathological assessment of granulomatous hepatitis: a retrospective study.
Liver granulomas (LG) are reported in 1-15% of liver biopsies and determining the aetiology can be challenging due to a wide range of aetiologies. The aim of this study was to describe the clinicopathological findings of LG. A retrospective review was performed of histopathological reports at South…
Clinical Characteristics, Diagnostic Features, and Medical Treatment of Sinonasal Sarcoidosis: A Systematic Review.
BackgroundSinonasal sarcoidosis (SNS) is an under-recognized manifestation of a multisystem granulomatous disease that often mimics common nasal inflammatory conditions, leading to diagnostic delays and uncertainty regarding optimal long-term management.ObjectiveThe purpose of this study was to revi…
Epidemiology and demographic trends of sarcoidosis in southern West Bank, Palestine: a retrospective study (2019-2024).
Sarcoidosis is a systemic granulomatous disease of unknown etiology that most commonly affects the lungs and hilar lymph nodes. Although it has been reported worldwide, its epidemiology and clinical characteristics in Palestine remain unclear. This study aimed to estimate the incidence, prevalence,…
Neurological involvement and pregnancy outcomes in autoimmune disease: mechanisms, clinical implications, and research gaps.
Pregnancy in systemic autoimmune diseases is associated with increased maternal and fetal morbidity, yet the specific impact of neurological involvement remains poorly characterized. This review synthesizes pregnancy outcomes in systemic lupus erythematosus (SLE), Sjögren's syndrome, sarcoidosi…