Abnormal expression of galectins and their correlation with fibrogenesis in adenomyosis.
This cross-sectional study investigated galectin-1, -3, and -9 in adenomyosis. Analysis of hysterectomy tissues from premenopausal women via western blot, qPCR, immunohistochemistry, and Masson's staining revealed significantly elevated galectin levels compared to controls. Galectin expression posit…
Clinical analysis of 8 cases of interstitial pregnancy after embryo transfer.
This study aimed to improve the diagnosis and treatment of intramural pregnancy (IMP). A retrospective analysis was conducted of 8 cases of IMP admitted between November 2016 and June 2024. Data on patients' clinical characteristics, diagnosis, treatment, and prognosis were systematically reviewed.…
Serum progesterone concentrations at frozen embryo transfer in women with adenomyosis and endometriosis: a retrospective cohort study.
Endometriosis and adenomyosis are estrogen-dependent inflammatory conditions frequently associated with impaired fertility. Although progesterone resistance at the tissue level is well documented, it remains unclear whether these conditions are associated with altered systemic progesterone exposure…
The effects of endometrial polyps, leiomyomas, adenomyosis, and endometriosis on endometrial receptivity: phenotype, molecular pathways, and clinical implications.
This review synthesizes current evidence on how endometrial polyps, leiomyomas, adenomyosis, and endometriosis influence endometrial receptivity, emphasizing phenotype-specific effects, molecular mechanisms, and implications for embryo transfer outcomes. Impaired endometrial receptivity, when presen…
Ultrasound-guided radiofrequency ablation of an intramural fibroid in a woman desiring fertility with coexisting focal adenomyosis: a case report.
To report the reproductive outcome after ultrasound-guided radiofrequency ablation (RFA) in a woman with an intramural uterine fibroid and coexisting focal adenomyosis who experienced infertility and desired pregnancy. Case report. A 40-year-old nulligravid woman with heavy menstrual bleeding, dysme…
Inhibition of Sonic Hedgehog signaling pathway by GANT61 alleviates adenomyosis by suppressing epithelial-to-mesenchymal transition, cell migration and proliferation.
Adenomyosis (ADM) is a benign condition associated with various gynecological disorders. However, effective treatment options are limited, highlighting the urgent need for novel therapeutic targets. This study identified abnormal activation of Hedgehog signaling pathway in tamoxifen-induced ADM mice…
An atypical case of adenomyosis coexisting with simple endometrial hyperplasia: A case report.
Adenomyosis and simple endometrial hyperplasia are common benign gynecological conditions. However, atypical presentations with extreme endometrial thickening and associated diagnostic challenges have rarely been reported. A 27-year-old woman presented with a 13-year history of menstrual irregularit…
Three-Port, Assistant-Port-Free Robotic Hysterectomy for a Large Adenomyotic Uterus with Multiple Fibroids: A Feasibility Case Report.
Large uteri with multiple fibroids or adenomyosis present significant challenges for minimally invasive surgery due to increased vascularity, distorted pelvic anatomy, and limited working space. While robotic platforms enhance precision through improved dexterity and vision, most surgeons still rely…