Abnormal expression of galectins and their correlation with fibrogenesis in adenomyosis.
This cross-sectional study investigated galectin-1, -3, and -9 in adenomyosis. Analysis of hysterectomy tissues from premenopausal women via western blot, qPCR, immunohistochemistry, and Masson's staining revealed significantly elevated galectin levels compared to controls. Galectin expression posit…
Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report.
Primary vaginal cancer is a rare malignant tumor; its pathogenesis remains unclear and only a limited number of cases have been documented in the literature. The present report outlines a rare case of primary vaginal endometrioid adenocarcinoma that occurred in a patient 3 years after a total hyster…
Adenomyosis and fertility: from pathophysiology to optimizing reproductive outcomes.
Adenomyosis is increasingly diagnosed in reproductive-aged patients, particularly those undergoing assisted reproductive technology, due to advances in imaging and standardized diagnostic criteria. Its association with infertility and adverse obstetric outcomes has prompted growing interest in under…
Focal and Diffuse Adenomyomectomy: A Systematic Review of Comparative Outcomes from Published Studies Including 3397 Patients.
To compare focal and diffuse adenomyomectomy in terms of clinical characteristics, surgical complexity, postoperative outcomes, and reproductive results. PubMed/MEDLINE, Web of Science, and Embase databases were searched from inception to October 2025 using keywords including "adenomyosis," "adenomy…
Development and validation of a clinical prediction model for the success of focused ultrasound ablation system for the treatment of adenomyosis.
This study aimed to develop and validate a clinical prediction model for the success of the focused ultrasound ablation system (FUAS) in treating adenomyosis. A retrospective analysis was conducted on 250 patients from Qingdao Women and Children's Hospital (2019-2022). Patients were categorized into…
Risk of endometrial carcinoma in patients with atypical endometrial hyperplasia in a population of predominantly racial and ethnic minorities, a single institution study.
To identify clinicopathologic predictors of concurrent endometrial carcinoma (EC) and need for lymph node assessment at time of hysterectomy for atypical endometrial hyperplasia (AEH) in a minority-enriched population. Retrospective analysis of AEH cases treated definitively via hysterectomy at a si…
Clinical characteristics of hospitalized patients with benign gallbladder disease: a large-scale retrospective analysis.
Benign gallbladder disease, including gallstones, gallbladder polyps, and gallbladder adenomyosis, is one of the most common disorders of the digestive system worldwide and poses a substantial clinical and economic burden. Despite its high prevalence, the clinical characteristics and risk profiles o…