Neonatal Hyperthyroidism: Case Report and Literature Review.
Fetal and neonatal hyperthyroidism are rare, but severe, conditions caused by transplacental passage of thyrotropin receptor antibodies from a pregnant patient with current or past Graves disease. We present the case of a late preterm infant who developed thyrotoxicosis secondary to maternal Graves…
Surgical considerations for adult Graves' disease: a narrative review of indications, perioperative challenges and postoperative outcomes.
Graves' disease (GD) is a systemic autoimmune disorder, ultimately caused by autoantibodies stimulating the TSH receptor (TSHR-Ab) on thyroid follicular cells. Novel targeted therapies are under investigation, but treatment of GD still relies on antithyroid drugs (ATDs), radioactive iodine, or thyro…
Differentiating TRAb-positive painless thyroiditis from Graves' disease using biochemical and ultrasound findings.
Differentiating painless thyroiditis (PT) from Graves' disease (GD) is important for appropriate management. This study evaluated whether thyroid-stimulating hormone (TSH) receptor antibody (TRAb)-positive PT can be differentiated from GD using biochemical and ultrasound findings. This retrospective…
Autoimmune diseases and risk of adverse pregnancy outcomes: a population-based cohort study of five million pregnancies in the UK.
With an increasing trend in the prevalence of maternal autoimmune diseases in pregnancy, there is need for evidence on the association between autoimmune diseases and pregnancy outcomes. This population-based cohort study used data on pregnancies from primary care practices that contributed to the U…
Late-onset Graves' disease after hemithyroidectomy: a case report.
Among hyperthyroidism cases, Graves' disease is the most common, with incidence peaking between 30 and 60 years of age. Hemithyroidectomy is sometimes performed for conditions such as thyroid tumors, and Graves' disease may develop from the residual thyroid tissue postoperatively. The occurrenc…
Investigating the Therapeutic Effect and Mechanism of Astragalus Mongholicus on Graves' Disease through Network Pharmacology.
Current treatments for Graves' disease have limitations, while emerging evidence suggests astragalus may modify disease progression. However, its precise mechanisms remain unclear. This study aims to systematically investigate the pharmacological basis of astragalus against Graves' disease, providin…
Response to comment on "Graves' disease-associated dopaminergic system dysfunction and its effects on striatocortical functional connectivity and cognitive function".
Atrial fibrillation as the initial presentation of hyperthyroidism: Two cases: Graves' thyroid storm and toxic adenoma.
Atrial fibrillation (AF) is a recognised but potentially reversible manifestation of hyperthyroidism and may occasionally precede classic thyrotoxic symptoms. We report two cases in which AF was the initial presentation of hyperthyroidism with distinct aetiology and clinical severity. The first had…