[Reproducibility of lesion stiffness measured by shear wave elastography in Hashimoto's thyroiditis combined with thyroid cancer and its correlation with pathological features].
Objective:To analyze the repeatability of shear wave imaging（SWE） to measure hardness of Hashimoto thyroiditis（HT） complicated with thyroid cancer（TC）, and the relationship between hardness and pathological features. Methods:This study enrolled 90 patients w…
Tetrahedral Framework Nucleic Acids Re-establish Immune Tolerance and Restore Thyroid Function in Hashimoto's Thyroiditis via NOTCH1 Signaling Pathway Inhibition.
Hashimoto's thyroiditis (HT) is a chronic autoimmune disorder in which persistent immune dysregulation gradually impairs thyroid structure and endocrine function. Although levothyroxine replacement can correct hypothyroidism, it has little effect on the underlying autoimmune activity that drives the…
Association between thyroid peroxidase antibodies and rheumatoid arthritis: insights from genetic and population-based evidence.
Rheumatoid arthritis (RA) has long been observed to co-occur with Hashimoto's thyroiditis, a condition characterized by the presence of thyroid peroxidase antibody (TPOAb); however, the specific contribution of TPOAb to RA pathogenesis remains unclear. Therefore, we aimed to investigate the associat…
From suspected lymphoma to self-limiting lymphadenitis: Kikuchi-Fujimoto disease in focus.
Kikuchi-Fujimoto disease (KFD) is a rare, self-limiting form of necrotizing lymphadenitis that primarily affects young adults and often mimics lymphoma or autoimmune lymphadenitis both clinically and histologically. We report the case of a 28-year-old Caucasian woman with a history of Hashimoto's th…
The clinical significance of SIGLEC1 mRNA levels derived from peripheral leukocytes in autoimmune thyroid diseases and type 1 diabetes.
Autoimmune thyroid diseases (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), may coexist with Type 1 diabetes mellitus (T1DM) as autoimmune polyglandular syndrome type 3 (APS3). Sialic acid-binding immunoglobulin-like lectin (SIGLEC) 1 is an interferon-inducible molecule impl…
Keratoconus: an ocular manifestation of systemic immune dysregulation?
Keratoconus is a corneal ectatic disorder traditionally considered non-inflammatory, but emerging evidence suggests immune system involvement. This study evaluates the epidemiological relationship between keratoconus and immune-mediated diseases in the Eastern Anatolian population. In this retrospec…
Late-onset Graves' disease after hemithyroidectomy: a case report.
Among hyperthyroidism cases, Graves' disease is the most common, with incidence peaking between 30 and 60 years of age. Hemithyroidectomy is sometimes performed for conditions such as thyroid tumors, and Graves' disease may develop from the residual thyroid tissue postoperatively. The occurrenc…
A Case Report of a Patient with Thyroid eye disease Induced by Hashimoto's Thyroiditis.
Autoimmune thyroid diseases (AITD) result from immune system dysregulation. Among them are Hashimoto's thyroiditis, Graves' disease, etc. Approximately 3% of patients with Hashimoto's thyroiditis may develop orbitopathy. Thyroid eye disease (TED), is an organ-specific autoimmune reaction that primar…