Proliferative myositis of the biceps brachii: A sarcoma mimicker.
Proliferative myositis is a rare benign intramuscular inflammatory pseudotumor that may clinically mimic a soft tissue sarcoma due to its rapid growth and painful presentation. We report the case of a 50-year-old man presenting with a rapidly enlarging, firm, and painful mass of the left arm, which…
Case of concurrent ALS and human T-cell leukaemia virus type 1-associated myositis.
A woman in her late 70s presented with progressive limb weakness, muscle atrophy and hyper-reflexia. Laboratory findings revealed elevated creatine kinase and positive serum human T-cell leukaemia virus type 1 (HTLV-1) antibody. Clinical and electrophysiological findings met revised El Escorial crit…
Inflammatory myopathies with anti-TIF1γ antibodies and their association with neoplasms: a study of a series of 28 cases.
To describe the clinical, immunological, and evolutionary profile of patients with anti-TIF1γ-positive inflammatory myopathy and to analyze its association with neoplasms. Retrospective study of patients with inflammatory myopathy and positive anti-TIF1γ antibodies treated at a tertiary…
Profiling Immune-Related Adverse Events Associated with Imatinib: A Two-Decade Real-World Safety Study Based on FDA Adverse Event Reporting System.
Emerging evidence suggests that imatinib may influence immune pathways and be associated with adverse events (AE) with potential immune involvement, some leading to treatment interruption or irreversible damage. However, systematic characterization remains limited. We analyzed FDA Adverse Event Repo…
Autoimmune Disease Risk With GLP-1RA, DPP-4i, and SGLT2i Treatment in Patients With Diabetes.
Dipeptidyl peptidase-4 inhibitors (DPP-4i), glucagon-like peptide-1 receptor agonists (GLP-1RA), and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are widely used for type 2 diabetes, yet their comparative immunologic safety is uncertain. To address this gap, we evaluated autoimmune disease inc…
Nailfold Videocapillaroscopy in Pediatric Rheumatology: Established Roles, Emerging Applications, and Future Perspectives.
Nailfold videocapillaroscopy (NVC) provides direct, non-invasive access to the peripheral microcirculation and has become a central tool in adult rheumatology. Its primary clinical value lies in the evaluation of patients presenting with signs of Raynaud phenomenon (RP) and scleroderma-spectrum diso…
Multifocal tuberculous myositis: a case series from a tuberculosis endemic region.
Multifocal tubercular myositis is rare but important entity that often mimics autoimmune rheumatic or inflammatory muscle diseases. This study aims to collect and analyse cases of multifocal muscular tuberculosis (TB) reported in tertiary care settings in India. This retrospective, multicentre, obse…
International Myositis Assessment and Clinical Studies Guidelines for Risk-Based Cancer Screening: An External Validation in Patients With Dermatomyositis Seen at a Metropolitan Academic Center.
Dermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) characterized by muscle weakness, skin findings, and increased malignancy risk. Cancer risk is greatest in the three years before or after DM onset, termed paraneoplastic DM. The International Myositis Assessment and Clinical Studies…