Cytotoxic Lesion of the Corpus Callosum After Hospital-Administered Intravenous Fentanyl for Trigeminal Neuralgia: A Case Report and Focused Review.
Fentanyl-associated neurotoxicity is increasingly recognized across illicit, inhalational, transdermal, pediatric, and delayed posthypoxic exposures, but isolated splenial CLOCC after hospital-administered intravenous fentanyl has not been well characterized. This is a single-patient case report wit…
A meta-analysis of pain intensity changes after placebo interventions in facial pain.
Interpreting pain improvements after interventions in clinical settings is challenging because placebo effects can influence patient-reported outcomes. In clinical practice, pain intensity reductions of 30% or greater are commonly considered indicative of meaningful analgesic benefit. However, the l…
CT imaging-led diagnosis of Parry-Romberg syndrome: A case report and literature review highlighting craniofacial and neurologic involvement.
Parry-Romberg syndrome (PRS) is a rare neurocutaneous disorder characterized by progressive unilateral facial atrophy involving soft tissues, fat, muscle, and sometimes underlying bone and brain tissue. The exact cause remains unclear, although autoimmune, neurogenic, vascular, traumatic, and inflam…
Motor-related white matter tracts are prominently affected in primary trigeminal neuralgia.
Primary trigeminal neuralgia (PTN) is a severe chronic pain disorder, yet whole-brain white matter microstructural alterations beyond the trigeminal nerve remain poorly understood, partly due to limitations of conventional diffusion tensor imaging in crossing fiber regions. We prospectively enrolled…
Division Specific Biologically Effective Dose Predicts Gamma Knife Radiosurgery Outcomes in Multiple Sclerosis-Associated Trigeminal Neuralgia.
Outcomes after Gamma Knife surgery (GKS) for multiple sclerosis-related trigeminal neuralgia type 1 (MS-TN1) remain variable, and the role of biologically effective dose (BED) distribution across trigeminal nerve subregions is not well defined. This study evaluated whether BED-based volumetric param…
Assessment of the accuracy and feasibility of CT fusion with real-time US guidance for percutaneous radiofrequency trigeminal rhizotomy.
To quantitatively assess the spatial accuracy and technical feasibility of computed tomography (CT) fusion with real-time ultrasound (US) guidance (CTF-USG) for percutaneous radiofrequency trigeminal rhizotomy (PRF-TR) in patients with trigeminal neuralgia (TN). This prospective observational study…
The efficacy of surgical interventions for trigeminal neuralgia in multiple sclerosis: A systematic review.
Trigeminal neuralgia affects approximately 3% of patients with multiple sclerosis - a far higher prevalence than in the general population. The associated pain often proves refractory to medication, prompting consideration of neurosurgical intervention. The variable efficacy, tolerability, and durab…