Suicidal ideation among patients with facial pain disorders.
Facial pain can be severely debilitating. Although etiologies vary, facial pain commonly results in diminished quality of life and a pronounced psychosocial burden. To determine whether severe facial pain is associated with a heightened risk of suicidal ideation. We performed a retrospective review…
Trigeminal root dislocation subtends focal demyelination of primary trigeminal afferents in patients with trigeminal neuralgia.
Trigeminal neuralgia (TN) is a neuropathic pain condition associated with focal demyelination of primary trigeminal afferents. Although MRI is routinely used in TN, the specific anatomical abnormality of the trigeminal root that reflects focal demyelination remains unclear. In this combined clinical…
Causal association between gut microbiota and trigeminal neuralgia: A bidirectional two-sample Mendelian randomization analysis.
An increasing number of studies have found associations between the gut microbiota (GM) and neurological disorders. However, the causal relationship between the GM and trigeminal neuralgia (TN) remains unclear. Mendelian randomization (MR) is an effective method to link pathological changes in dista…
A modified FLIT-B model of trigeminal neuralgia reveals anterior cingulate cortex involvement in anxiety-like behavior in mice.
Trigeminal neuralgia (TN) is a debilitating orofacial pain disorder characterized by paroxysmal, lancinating pain and prominent affective comorbidities. Increasing evidence suggests that chronic TN involves abnormal plasticity in supraspinal pain circuits. However, the lack of animal models that fai…
Stereotactic radiosurgery for trigeminal neuralgia secondary to vertebrobasilar dolichoectasia: A systematic review and meta-analysis.
Trigeminal neuralgia (TN) secondary to vertebrobasilar dolichoectasia (VBD) is a rare and surgically challenging condition due to the complex anatomy and elevated risks of open craniotomies. Stereotactic radiosurgery (SRS) offers a minimally invasive alternative, but evidence has been limited to sma…
The CSF sign - A potential biomarker in ophthalmic neuralgia?
Specific magnetic resonance imaging sequences are utilized in the visualization of the detailed morphology of neurovascular compression (NVC) in classic trigeminal neuralgia (TN). This study focuses on essential morphological parameters especially in the clinical involvement of the ophthalmic branch…
Trigeminocerebellar artery as a subsequent offending vessel for recurrent trigeminal neuralgia after initial microvascular decompression: illustrative case.
The most common cause of trigeminal neuralgia (TN) is vascular compression at the root entry zone of the trigeminal nerve, most frequently by the superior cerebellar artery (SCA). Trigeminocerebellar artery (TCA) involvement in TN is rare, and its management with microvascular decompression (MVD) ha…
Trigeminal Neuralgia After a Cerebrospinal Fluid Leak: A Case Report.
Cerebrospinal fluid (CSF) leakage can be difficult to localize and may result in unexplained intracranial hypotension with intractable positional headache. Loss of CSF cushioning can cause brain sagging, leading to compression and traction of cranial nerves within the brain cisterns and mimicking Ch…