Painful tic convulsif: Dual neurovascular compression within the spectrum of cranial nerve hyperactive dysfunction syndromes.
Concurrent trigeminal neuralgia (TN) and hemifacial spasm (HFS), historically termed painful tic convulsif, is a rare manifestation of cranial nerve hyperactive dysfunction associated with neurovascular compression. The operative anatomy may involve independent conflicts affecting cranial nerves V a…
Efficacy and safety of microvascular decompression versus gamma knife surgery in patients with trigeminal neuralgia: an updated meta-analysis.
Trigeminal neuralgia(TN) is a debilitating condition often requiring surgical intervention when medical therapy fails. Microvascular decompression (MVD) and Gamma Knife surgery (GKS) are the main treatment options, but their relative efficacy and safety remain debated. This meta-analysis aimed to co…
Gabapentinoids for Neuropathic Pain Management: A Systematic Umbrella Review.
This umbrella review aimed to evaluate the effectiveness of gabapentinoids, including dosing and risk profile, for the management of neuropathic pain. Eligibility criteria were restricted exclusively to systematic reviews and meta-analyses conducted under PRISMA reporting standards. Methodological q…
Proton Density MRI for Evaluation of Neurovascular Structures Involved in Trigeminal Neuralgia.
Classical trigeminal neuralgia is attributed to vascular compression of the trigeminal nerve root entry zone. High resolution heavily T2 weighted sequences provide excellent contrast between CSF and neurovascular structures. However, they demonstrate poor contrast between nerves and vessels, confoun…
Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews.
BACKGROUND AND OBJECTIVE: Trigeminal neuralgia (TN) and postherpetic neuralgia (PHN) are severe peripheral neuropathic pain conditions associated with substantial functional impairment. Although pharmacological treatments are available, many patients experience insufficient efficacy or poor tol…
Carbamazepine-Induced Drug-Induced Hypersensitivity Syndrome With Primary Adrenal Insufficiency: A Case Report.
Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms, is a severe adverse reaction involving multiple organs. We describe a case of carbamazepine (CBZ)-induced DIHS with rare primary endocrine complications. A 71-year-old Japanese man dev…
In Vivo confocal microscopy evaluation of corneal layer alterations in patients with trigeminal neuralgia.
PurposeTo investigate corneal microstructural alterations in patients with trigeminal neuralgia using in vivo confocal microscopy and to compare these findings with healthy controls.MethodsIn this prospective, cross-sectional study, sixty patients with unilateral trigeminal neuralgia and sixty match…
Targeting neurovascular conflict in atypical vagal-glossopharyngeal neuralgia: illustrative case.
Vagal-glossopharyngeal neuralgia (VGPN) represents a rare and often misdiagnosed condition. Compared to the more common trigeminal neuralgia, its clinical picture is more heterogeneous due to the multiple functions exerted by the rootlets involved; indeed, presentation may include dysphagia, dysphon…